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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP4 All Species: 1.21
Human Site: S371 Identified Species: 2.96
UniProt: Q96P64 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.56
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P64 NP_597703.2 663 73070 S371 P K L N P P P S P H A N K K K
Chimpanzee Pan troglodytes XP_001141446 439 48772 K153 P S P H A N K K K H L K K K S
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 K486 K K S T S N F K A D G L S G T
Dog Lupus familis XP_848466 936 102470 K618 K K S T S N F K A D G L S G T
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 K539 K K S T S N F K A D G L S G T
Rat Rattus norvegicus Q8CGU4 1186 124419 K855 K R K M W K L K S F G S L R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRL1 864 95088 K542 K K S T S N F K V D G L S S T
Zebra Danio Brachydanio rerio Q08CI4 339 38765 D52 S D R E V P D D L A L E S N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 M632 V K K R H R R M K S S S V K A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5W7F2 827 92506 S431 K I T G V I A S L L S S Q V P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.2 56.3 50 N.A. 52.6 28.2 N.A. N.A. N.A. 48.6 22.3 N.A. 29.5 N.A. N.A. N.A.
Protein Similarity: 100 64.5 66.9 58.7 N.A. 62.4 39.2 N.A. N.A. N.A. 59.8 34.2 N.A. 41.7 N.A. N.A. N.A.
P-Site Identity: 100 26.6 6.6 6.6 N.A. 6.6 0 N.A. N.A. N.A. 6.6 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 6.6 6.6 N.A. 6.6 20 N.A. N.A. N.A. 6.6 6.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 30 10 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 10 10 0 40 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 40 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 50 0 0 30 0 % G
% His: 0 0 0 10 10 0 0 0 0 20 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 60 60 20 0 0 10 10 60 20 0 0 10 20 30 10 % K
% Leu: 0 0 10 0 0 0 10 0 20 10 20 40 10 0 0 % L
% Met: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 50 0 0 0 0 0 10 0 10 10 % N
% Pro: 20 0 10 0 10 20 10 0 10 0 0 0 0 0 20 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 10 10 10 0 10 10 0 0 0 0 0 0 10 0 % R
% Ser: 10 10 40 0 40 0 0 20 10 10 20 30 50 10 10 % S
% Thr: 0 0 10 40 0 0 0 0 0 0 0 0 0 0 40 % T
% Val: 10 0 0 0 20 0 0 0 10 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _