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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP4 All Species: 25.15
Human Site: S437 Identified Species: 61.48
UniProt: Q96P64 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P64 NP_597703.2 663 73070 S437 K S K S Q L T S Q S K A M A L
Chimpanzee Pan troglodytes XP_001141446 439 48772 A219 T S Q S E A M A L Q L I Q N M
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 S552 K N K S R L T S Q S E A M A L
Dog Lupus familis XP_848466 936 102470 S684 K N K S R L T S Q S E A M A L
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 S605 K N K S R L T S Q S E A M A L
Rat Rattus norvegicus Q8CGU4 1186 124419 S921 K V K L R T D S Q S E A V A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRL1 864 95088 S608 K N K S R L T S Q N E A L A L
Zebra Danio Brachydanio rerio Q08CI4 339 38765 S118 V S Q P N L K S T I K C V T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 S698 S K T K Q A T S T D L A A M L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5W7F2 827 92506 I497 S F Q P Q R S I R K G E K P I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.2 56.3 50 N.A. 52.6 28.2 N.A. N.A. N.A. 48.6 22.3 N.A. 29.5 N.A. N.A. N.A.
Protein Similarity: 100 64.5 66.9 58.7 N.A. 62.4 39.2 N.A. N.A. N.A. 59.8 34.2 N.A. 41.7 N.A. N.A. N.A.
P-Site Identity: 100 13.3 80 80 N.A. 80 46.6 N.A. N.A. N.A. 66.6 33.3 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 73.3 N.A. N.A. N.A. 100 46.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 20 0 10 0 0 0 70 10 60 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 50 10 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 10 0 10 0 0 20 % I
% Lys: 60 10 60 10 0 0 10 0 0 10 20 0 10 0 0 % K
% Leu: 0 0 0 10 0 60 0 0 10 0 20 0 10 0 70 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 40 10 10 % M
% Asn: 0 40 0 0 10 0 0 0 0 10 0 0 0 10 0 % N
% Pro: 0 0 0 20 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 30 0 30 0 0 0 60 10 0 0 10 0 0 % Q
% Arg: 0 0 0 0 50 10 0 0 10 0 0 0 0 0 0 % R
% Ser: 20 30 0 60 0 0 10 80 0 50 0 0 0 0 0 % S
% Thr: 10 0 10 0 0 10 60 0 20 0 0 0 0 10 0 % T
% Val: 10 10 0 0 0 0 0 0 0 0 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _