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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGAP4
All Species:
1.21
Human Site:
T216
Identified Species:
2.96
UniProt:
Q96P64
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P64
NP_597703.2
663
73070
T216
S
V
P
P
T
A
N
T
P
T
P
V
C
K
R
Chimpanzee
Pan troglodytes
XP_001141446
439
48772
Rhesus Macaque
Macaca mulatta
XP_001082744
804
89081
K331
S
D
P
D
K
E
K
K
G
L
E
S
R
A
D
Dog
Lupus familis
XP_848466
936
102470
L463
V
L
T
Y
H
P
S
L
H
D
Y
M
Q
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXK8
857
94393
L384
V
L
T
Y
H
P
S
L
H
D
Y
M
Q
N
V
Rat
Rattus norvegicus
Q8CGU4
1186
124419
G700
Y
V
T
L
S
S
N
G
F
L
L
Y
H
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRL1
864
95088
Y387
Y
H
P
S
L
H
D
Y
M
Q
N
V
H
G
K
Zebra Danio
Brachydanio rerio
Q08CI4
339
38765
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NGC3
995
108026
V477
K
E
W
K
K
K
Y
V
T
L
C
D
D
G
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5W7F2
827
92506
H276
Q
A
I
G
R
S
S
H
K
M
I
D
A
V
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.2
56.3
50
N.A.
52.6
28.2
N.A.
N.A.
N.A.
48.6
22.3
N.A.
29.5
N.A.
N.A.
N.A.
Protein Similarity:
100
64.5
66.9
58.7
N.A.
62.4
39.2
N.A.
N.A.
N.A.
59.8
34.2
N.A.
41.7
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
0
N.A.
0
13.3
N.A.
N.A.
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
13.3
20
N.A.
20
26.6
N.A.
N.A.
N.A.
26.6
0
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% C
% Asp:
0
10
0
10
0
0
10
0
0
20
0
20
10
0
10
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
10
0
0
0
0
20
0
% G
% His:
0
10
0
0
20
10
0
10
20
0
0
0
20
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
10
0
0
10
20
10
10
10
10
0
0
0
0
10
10
% K
% Leu:
0
20
0
10
10
0
0
20
0
30
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
20
0
0
10
% M
% Asn:
0
0
0
0
0
0
20
0
0
0
10
0
0
20
0
% N
% Pro:
0
0
30
10
0
20
0
0
10
0
10
0
0
10
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
10
0
0
20
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
20
% R
% Ser:
20
0
0
10
10
20
30
0
0
0
0
10
0
0
10
% S
% Thr:
0
0
30
0
10
0
0
10
10
10
0
0
0
0
0
% T
% Val:
20
20
0
0
0
0
0
10
0
0
0
20
0
10
20
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
20
0
0
10
10
0
0
20
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _