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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR78
All Species:
4.55
Human Site:
S74
Identified Species:
12.5
UniProt:
Q96P69
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P69
NP_543009.2
363
39332
S74
V
M
R
G
R
T
P
S
A
P
G
A
C
Q
V
Chimpanzee
Pan troglodytes
XP_526521
363
39203
S74
V
M
R
G
R
T
P
S
A
P
G
A
C
Q
V
Rhesus Macaque
Macaca mulatta
Q8HYC3
389
42108
A70
V
V
G
V
V
G
N
A
Y
T
L
V
V
T
C
Dog
Lupus familis
XP_544056
337
37525
M60
L
L
C
T
V
L
N
M
P
L
T
L
A
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZA7
337
37728
M60
L
L
C
T
V
V
N
M
P
L
T
L
A
G
V
Rat
Rattus norvegicus
Q9QXI3
337
37786
M60
L
L
C
T
V
V
N
M
P
L
T
L
A
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518463
399
44499
A74
L
L
T
G
R
S
P
A
G
D
R
L
C
Q
A
Chicken
Gallus gallus
XP_426354
339
38950
M60
L
L
L
T
I
L
N
M
P
F
T
L
L
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340163
339
38867
M60
I
L
I
S
V
L
N
M
P
S
T
L
F
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
20.3
48.7
N.A.
46.8
46.8
N.A.
46.1
52.3
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
33.9
64.4
N.A.
63
63.3
N.A.
61.4
69.1
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
6.6
N.A.
33.3
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
20
20
N.A.
60
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
23
23
0
0
23
34
0
12
% A
% Cys:
0
0
34
0
0
0
0
0
0
0
0
0
34
0
12
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% F
% Gly:
0
0
12
34
0
12
0
0
12
0
23
0
0
56
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
12
0
12
0
0
0
0
0
0
0
0
0
23
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
56
67
12
0
0
34
0
0
0
34
12
67
12
0
0
% L
% Met:
0
23
0
0
0
0
0
56
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
34
0
56
23
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% Q
% Arg:
0
0
23
0
34
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
0
0
0
12
0
12
0
23
0
12
0
0
0
0
0
% S
% Thr:
0
0
12
45
0
23
0
0
0
12
56
0
0
12
0
% T
% Val:
34
12
0
12
56
23
0
0
0
0
0
12
12
0
56
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _