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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IPO9 All Species: 18.18
Human Site: S464 Identified Species: 28.57
UniProt: Q96P70 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P70 NP_060555.2 1041 115963 S464 V K A I I T D S V K N G R I H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108417 1041 115930 S464 V K A I I T D S V K N G R I H
Dog Lupus familis XP_537126 990 111036 N436 N V I L A D L N L S V S P F L
Cat Felis silvestris
Mouse Mus musculus Q91YE6 1041 116033 S464 V K S I I T D S V K N G R I H
Rat Rattus norvegicus NP_001100650 1041 115993 S464 V K S I I T D S V K N G R I H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508457 1350 147771 S774 V K S I I T D S V K N G R V H
Chicken Gallus gallus XP_419247 999 111832 R429 T D S V K N G R I H F D M H G
Frog Xenopus laevis NP_001087649 1033 115448 G458 V K S V I I E G V Q S G R V Q
Zebra Danio Brachydanio rerio NP_998704 1043 115572 V466 K T I I T E N V K N G R V Q F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650068 1018 114389 A457 A F R D V I L A G D S T F D L
Honey Bee Apis mellifera XP_624403 1032 116227 G458 V V E R Q Q T G I L Q F D I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795786 1041 115626 K455 I K S L I I D K V G K G K L T
Poplar Tree Populus trichocarpa XP_002312347 928 102861 G387 V N S F G S E G I Y A I I D A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173942 1022 113450 D453 D Q L V E A E D L R I D P A N
Baker's Yeast Sacchar. cerevisiae P53067 1004 113903 Q436 E N I D Q S L Q I L I K T L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.9 94.7 N.A. 99 99 N.A. 73.3 90.3 85.4 85.2 N.A. 36.7 49.9 N.A. 59.3
Protein Similarity: 100 N.A. 100 95 N.A. 99.5 99.4 N.A. 75.6 93.9 91.6 93 N.A. 57.3 68.4 N.A. 76.6
P-Site Identity: 100 N.A. 100 0 N.A. 93.3 93.3 N.A. 86.6 0 40 6.6 N.A. 0 13.3 N.A. 33.3
P-Site Similarity: 100 N.A. 100 20 N.A. 100 100 N.A. 100 20 80 13.3 N.A. 20 20 N.A. 66.6
Percent
Protein Identity: 27.4 N.A. N.A. 27.6 21 N.A.
Protein Similarity: 47.3 N.A. N.A. 51.2 42.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 0 N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 14 0 7 7 0 7 0 0 7 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 14 0 7 40 7 0 7 0 14 7 14 0 % D
% Glu: 7 0 7 0 7 7 20 0 0 0 0 0 0 0 7 % E
% Phe: 0 7 0 7 0 0 0 0 0 0 7 7 7 7 7 % F
% Gly: 0 0 0 0 7 0 7 20 7 7 7 47 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 34 % H
% Ile: 7 0 20 40 47 20 0 0 27 0 14 7 7 34 7 % I
% Lys: 7 47 0 0 7 0 0 7 7 34 7 7 7 0 0 % K
% Leu: 0 0 7 14 0 0 20 0 14 14 0 0 0 14 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 7 14 0 0 0 7 7 7 0 7 34 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % P
% Gln: 0 7 0 0 14 7 0 7 0 7 7 0 0 7 7 % Q
% Arg: 0 0 7 7 0 0 0 7 0 7 0 7 40 0 0 % R
% Ser: 0 0 47 0 0 14 0 34 0 7 14 7 0 0 0 % S
% Thr: 7 7 0 0 7 34 7 0 0 0 0 7 7 0 7 % T
% Val: 54 14 0 20 7 0 0 7 47 0 7 0 7 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _