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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IPO9 All Species: 31.82
Human Site: S553 Identified Species: 50
UniProt: Q96P70 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P70 NP_060555.2 1041 115963 S553 D Q L K V S E S T H V L Q P F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108417 1041 115930 S553 D Q L K V S E S T H V L Q P F
Dog Lupus familis XP_537126 990 111036 S525 I H L A A Q F S S E V L N L V
Cat Felis silvestris
Mouse Mus musculus Q91YE6 1041 116033 S553 D Q L K V S E S T H V L Q P F
Rat Rattus norvegicus NP_001100650 1041 115993 S553 D Q L K V S E S T H V L Q P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508457 1350 147771 S863 D Q L K I S E S S H V L R P F
Chicken Gallus gallus XP_419247 999 111832 Q518 S E S T H V L Q P F L P S I L
Frog Xenopus laevis NP_001087649 1033 115448 S547 D Q L K I S E S T H V L Q P F
Zebra Danio Brachydanio rerio NP_998704 1043 115572 S555 D Q L K L S E S T H V L Q P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650068 1018 114389 K546 N E T I D G E K R T L L V S K
Honey Bee Apis mellifera XP_624403 1032 116227 L547 M M E N N N T L G N I I R S H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795786 1041 115626 S544 E H L K G A N S T S I L I P F
Poplar Tree Populus trichocarpa XP_002312347 928 102861 K476 R I F T S V A K F S S V I S H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173942 1022 113450 I542 P D M N S S V I L P Q I M N L
Baker's Yeast Sacchar. cerevisiae P53067 1004 113903 V525 D S V L G P E V C S E T Q E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.9 94.7 N.A. 99 99 N.A. 73.3 90.3 85.4 85.2 N.A. 36.7 49.9 N.A. 59.3
Protein Similarity: 100 N.A. 100 95 N.A. 99.5 99.4 N.A. 75.6 93.9 91.6 93 N.A. 57.3 68.4 N.A. 76.6
P-Site Identity: 100 N.A. 100 26.6 N.A. 100 100 N.A. 80 0 93.3 93.3 N.A. 13.3 0 N.A. 46.6
P-Site Similarity: 100 N.A. 100 33.3 N.A. 100 100 N.A. 100 13.3 100 100 N.A. 33.3 33.3 N.A. 66.6
Percent
Protein Identity: 27.4 N.A. N.A. 27.6 21 N.A.
Protein Similarity: 47.3 N.A. N.A. 51.2 42.4 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 20 N.A.
P-Site Similarity: 6.6 N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 7 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 54 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 14 7 0 0 0 60 0 0 7 7 0 0 7 0 % E
% Phe: 0 0 7 0 0 0 7 0 7 7 0 0 0 0 54 % F
% Gly: 0 0 0 0 14 7 0 0 7 0 0 0 0 0 0 % G
% His: 0 14 0 0 7 0 0 0 0 47 0 0 0 0 14 % H
% Ile: 7 7 0 7 14 0 0 7 0 0 14 14 14 7 0 % I
% Lys: 0 0 0 54 0 0 0 14 0 0 0 0 0 0 14 % K
% Leu: 0 0 60 7 7 0 7 7 7 0 14 67 0 7 14 % L
% Met: 7 7 7 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 7 0 0 14 7 7 7 0 0 7 0 0 7 7 0 % N
% Pro: 7 0 0 0 0 7 0 0 7 7 0 7 0 54 0 % P
% Gln: 0 47 0 0 0 7 0 7 0 0 7 0 47 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 7 0 0 0 14 0 0 % R
% Ser: 7 7 7 0 14 54 0 60 14 20 7 0 7 20 0 % S
% Thr: 0 0 7 14 0 0 7 0 47 7 0 7 0 0 0 % T
% Val: 0 0 7 0 27 14 7 7 0 0 54 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _