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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF17
All Species:
13.64
Human Site:
S1192
Identified Species:
37.5
UniProt:
Q96PE2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PE2
NP_055601.2
2063
221673
S1192
F
L
K
F
L
E
Q
S
M
R
E
N
K
E
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115376
2068
222292
S1197
F
L
K
F
L
E
Q
S
M
R
E
N
K
E
K
Dog
Lupus familis
XP_851853
1977
212581
A1155
D
H
P
L
L
L
D
A
Q
R
N
I
K
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80U35
2057
221653
S1185
F
L
K
F
L
E
Q
S
M
R
E
N
K
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417257
744
80606
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665334
2317
255368
S1455
F
L
K
F
L
E
Q
S
M
R
E
N
R
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397003
1717
186459
I937
T
W
E
L
K
Q
T
I
G
D
V
F
L
D
V
Nematode Worm
Caenorhab. elegans
Q21653
1182
132752
V401
T
L
I
E
A
S
L
V
D
K
I
F
Y
R
I
Sea Urchin
Strong. purpuratus
XP_795658
991
109650
L211
Y
E
L
L
L
K
E
L
I
D
N
T
A
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
86.8
N.A.
87.1
N.A.
N.A.
N.A.
23.7
N.A.
47.1
N.A.
N.A.
29.5
21.1
24.3
Protein Similarity:
100
N.A.
96.6
89.7
N.A.
90.6
N.A.
N.A.
N.A.
30
N.A.
59.7
N.A.
N.A.
44.3
34.3
34.5
P-Site Identity:
100
N.A.
100
20
N.A.
100
N.A.
N.A.
N.A.
0
N.A.
93.3
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
N.A.
100
33.3
N.A.
100
N.A.
N.A.
N.A.
0
N.A.
100
N.A.
N.A.
20
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
12
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
12
0
12
23
0
0
0
23
12
% D
% Glu:
0
12
12
12
0
45
12
0
0
0
45
0
0
45
0
% E
% Phe:
45
0
0
45
0
0
0
0
0
0
0
23
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
12
12
0
12
12
0
0
12
% I
% Lys:
0
0
45
0
12
12
0
0
0
12
0
0
45
0
45
% K
% Leu:
0
56
12
34
67
12
12
12
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
23
45
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
45
0
12
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
56
0
0
12
12
0
% R
% Ser:
0
0
0
0
0
12
0
45
0
0
0
0
0
0
0
% S
% Thr:
23
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
23
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _