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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF17
All Species:
9.09
Human Site:
S251
Identified Species:
25
UniProt:
Q96PE2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PE2
NP_055601.2
2063
221673
S251
R
S
R
A
A
S
S
S
E
E
E
E
E
G
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115376
2068
222292
S256
R
S
R
A
A
S
S
S
E
E
E
E
E
G
P
Dog
Lupus familis
XP_851853
1977
212581
H255
G
A
Q
S
P
A
Y
H
G
G
H
S
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80U35
2057
221653
S250
R
S
R
A
A
S
S
S
E
E
E
E
E
G
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417257
744
80606
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665334
2317
255368
P369
G
R
T
G
G
K
F
P
Q
N
K
H
G
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397003
1717
186459
R73
S
Q
E
R
R
R
K
R
S
S
R
E
S
D
S
Nematode Worm
Caenorhab. elegans
Q21653
1182
132752
Sea Urchin
Strong. purpuratus
XP_795658
991
109650
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
86.8
N.A.
87.1
N.A.
N.A.
N.A.
23.7
N.A.
47.1
N.A.
N.A.
29.5
21.1
24.3
Protein Similarity:
100
N.A.
96.6
89.7
N.A.
90.6
N.A.
N.A.
N.A.
30
N.A.
59.7
N.A.
N.A.
44.3
34.3
34.5
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
N.A.
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
N.A.
100
33.3
N.A.
100
N.A.
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
6.6
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
34
34
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
12
0
0
0
0
0
34
34
34
45
34
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
23
0
0
12
12
0
0
0
12
12
0
0
12
45
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
12
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
12
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
34
% P
% Gln:
0
12
12
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
34
12
34
12
12
12
0
12
0
0
12
0
0
0
12
% R
% Ser:
12
34
0
12
0
34
34
34
12
12
0
12
23
0
23
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _