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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF17
All Species:
3.94
Human Site:
S493
Identified Species:
10.83
UniProt:
Q96PE2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PE2
NP_055601.2
2063
221673
S493
R
V
R
K
P
G
G
S
S
G
D
R
G
S
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115376
2068
222292
S498
R
V
R
K
P
G
G
S
P
G
D
R
V
S
S
Dog
Lupus familis
XP_851853
1977
212581
A493
L
L
L
A
G
P
S
A
E
E
D
P
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80U35
2057
221653
G487
L
R
V
R
K
P
S
G
G
P
G
N
R
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417257
744
80606
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665334
2317
255368
L616
P
D
I
A
S
E
T
L
S
L
L
S
Y
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397003
1717
186459
K308
R
E
L
T
E
K
L
K
G
P
A
P
V
P
P
Nematode Worm
Caenorhab. elegans
Q21653
1182
132752
Sea Urchin
Strong. purpuratus
XP_795658
991
109650
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
86.8
N.A.
87.1
N.A.
N.A.
N.A.
23.7
N.A.
47.1
N.A.
N.A.
29.5
21.1
24.3
Protein Similarity:
100
N.A.
96.6
89.7
N.A.
90.6
N.A.
N.A.
N.A.
30
N.A.
59.7
N.A.
N.A.
44.3
34.3
34.5
P-Site Identity:
100
N.A.
80
6.6
N.A.
0
N.A.
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
N.A.
86.6
20
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
23
0
0
0
12
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
34
0
0
0
0
% D
% Glu:
0
12
0
0
12
12
0
0
12
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
23
23
12
23
23
12
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
23
12
12
0
12
0
0
0
0
0
0
12
% K
% Leu:
23
12
23
0
0
0
12
12
0
12
12
0
12
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% N
% Pro:
12
0
0
0
23
23
0
0
12
23
0
23
0
34
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
34
12
23
12
0
0
0
0
0
0
0
23
12
0
0
% R
% Ser:
0
0
0
0
12
0
23
23
23
0
0
12
0
23
12
% S
% Thr:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% T
% Val:
0
23
12
0
0
0
0
0
0
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _