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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MACF1
All Species:
9.39
Human Site:
S374
Identified Species:
25.83
UniProt:
Q96PK2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PK2
NP_149033.2
5938
670151
S374
P
H
M
Q
L
A
D
S
A
E
Q
N
I
N
P
Chimpanzee
Pan troglodytes
XP_001170848
5940
670498
S374
P
H
M
Q
L
A
D
S
A
E
Q
N
I
N
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849152
5423
619404
T362
Q
Y
I
H
F
K
E
T
E
I
L
A
K
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXZ0
5327
607958
T362
Q
Y
I
H
F
K
E
T
E
I
L
A
K
E
R
Rat
Rattus norvegicus
NP_001129230
5430
619582
T362
Q
Y
I
H
F
K
E
T
E
I
L
A
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515630
7036
790279
E633
P
S
V
E
S
Q
L
E
T
Q
Q
H
I
H
T
Chicken
Gallus gallus
P11533
3660
422863
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920094
5393
611479
T363
E
Y
V
H
F
K
E
T
E
I
P
A
K
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195605
3054
349588
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
68.4
N.A.
64.5
66.6
N.A.
56.2
20.7
N.A.
43.7
N.A.
N.A.
N.A.
N.A.
23.6
Protein Similarity:
100
99.6
N.A.
76.7
N.A.
73.7
75.8
N.A.
67.9
36.3
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
36.2
P-Site Identity:
100
100
N.A.
0
N.A.
0
0
N.A.
20
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
26.6
26.6
N.A.
53.3
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
23
0
0
23
0
0
45
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
12
0
0
45
12
45
23
0
0
0
45
0
% E
% Phe:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
23
0
45
0
0
0
0
0
0
0
12
0
12
0
% H
% Ile:
0
0
34
0
0
0
0
0
0
45
0
0
34
0
0
% I
% Lys:
0
0
0
0
0
45
0
0
0
0
0
0
45
0
0
% K
% Leu:
0
0
0
0
23
0
12
0
0
0
34
0
0
0
0
% L
% Met:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
23
0
23
0
% N
% Pro:
34
0
0
0
0
0
0
0
0
0
12
0
0
0
23
% P
% Gln:
34
0
0
23
0
12
0
0
0
12
34
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% R
% Ser:
0
12
0
0
12
0
0
23
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
45
12
0
0
0
0
0
12
% T
% Val:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _