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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SORCS2
All Species:
9.7
Human Site:
S221
Identified Species:
30.48
UniProt:
Q96PQ0
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PQ0
NP_065828.2
1159
128152
S221
K
R
K
V
I
L
V
S
S
S
L
S
D
R
D
Chimpanzee
Pan troglodytes
XP_508026
1361
150846
T410
K
R
K
I
M
L
L
T
D
P
E
I
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001083180
1198
133392
T247
K
R
K
I
M
L
L
T
D
P
E
I
E
S
S
Dog
Lupus familis
XP_545903
1051
117467
E161
K
V
L
A
Y
T
K
E
N
K
L
Y
V
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPR5
1159
128854
S221
K
R
K
I
I
L
V
S
S
S
L
G
D
R
E
Rat
Rattus norvegicus
O54861
825
91151
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512681
1026
115376
L136
E
F
G
R
R
W
Q
L
I
Q
E
G
V
V
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NUT7
814
90962
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.2
45.1
76.2
N.A.
86.1
22.5
N.A.
42
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.1
63.1
82.1
N.A.
91.9
37.9
N.A.
59.9
N.A.
N.A.
35.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
26.6
13.3
N.A.
80
0
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
60
20
N.A.
93.3
0
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
25
0
0
0
25
0
13
% D
% Glu:
13
0
0
0
0
0
0
13
0
0
38
0
25
0
13
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
0
0
0
0
0
25
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
38
25
0
0
0
13
0
0
25
0
0
0
% I
% Lys:
63
0
50
0
0
0
13
0
0
13
0
0
0
0
0
% K
% Leu:
0
0
13
0
0
50
25
13
0
0
38
0
0
0
0
% L
% Met:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
13
% P
% Gln:
0
0
0
0
0
0
13
0
0
13
0
0
0
0
0
% Q
% Arg:
0
50
0
13
13
0
0
0
0
0
0
0
0
25
0
% R
% Ser:
0
0
0
0
0
0
0
25
25
25
0
13
0
38
38
% S
% Thr:
0
0
0
0
0
13
0
25
0
0
0
0
0
0
0
% T
% Val:
0
13
0
13
0
0
25
0
0
0
0
0
25
13
0
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _