KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGLEC12
All Species:
8.18
Human Site:
S569
Identified Species:
36
UniProt:
Q96PQ1
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PQ1
NP_201586.1
595
64984
S569
E
I
Q
Y
A
S
L
S
F
H
K
A
R
P
Q
Chimpanzee
Pan troglodytes
Q95LH0
597
65057
S571
E
I
Q
Y
A
S
L
S
F
H
K
A
R
P
Q
Rhesus Macaque
Macaca mulatta
XP_001116358
596
65528
S570
E
I
H
Y
A
F
L
S
F
H
K
V
R
P
Q
Dog
Lupus familis
XP_541460
697
77324
G627
Q
K
A
V
H
N
H
G
V
H
P
A
L
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91Y57
467
51871
P442
L
S
F
H
E
M
K
P
M
N
L
W
G
Q
Q
Rat
Rattus norvegicus
NP_001099719
568
62021
Q543
H
Y
A
S
L
S
F
Q
G
P
R
P
Q
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
83.7
44.3
N.A.
42.6
29.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
88
58.2
N.A.
55.2
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
26.6
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
50
0
0
0
0
0
0
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% D
% Glu:
50
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
17
0
0
17
17
0
50
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
17
17
0
0
0
17
0
0
% G
% His:
17
0
17
17
17
0
17
0
0
67
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
0
0
17
0
0
0
50
0
0
0
0
% K
% Leu:
17
0
0
0
17
0
50
0
0
0
17
0
17
0
0
% L
% Met:
0
0
0
0
0
17
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
0
17
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
17
0
17
17
17
0
50
17
% P
% Gln:
17
0
34
0
0
0
0
17
0
0
0
0
17
34
67
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
17
0
50
0
0
% R
% Ser:
0
17
0
17
0
50
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% T
% Val:
0
0
0
17
0
0
0
0
17
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% W
% Tyr:
0
17
0
50
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _