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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL5
All Species:
11.52
Human Site:
S170
Identified Species:
25.33
UniProt:
Q96PQ7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PQ7
NP_057074.3
755
84457
S170
E
E
E
N
E
S
D
S
S
S
C
R
T
S
N
Chimpanzee
Pan troglodytes
XP_517151
841
93132
S256
E
E
E
N
E
S
D
S
S
S
C
R
T
S
N
Rhesus Macaque
Macaca mulatta
XP_001090229
709
79149
E165
E
Q
T
F
K
K
M
E
N
Y
L
R
H
K
Q
Dog
Lupus familis
XP_851357
710
80049
E164
E
Q
T
F
K
K
M
E
N
Y
L
R
H
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI74
751
82914
G165
S
I
Q
A
T
G
E
G
C
G
H
R
L
T
S
Rat
Rattus norvegicus
Q8K430
640
69714
L108
I
R
A
H
K
V
V
L
A
S
C
S
P
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512881
889
97747
T304
E
E
E
N
E
S
D
T
S
S
C
R
T
S
N
Chicken
Gallus gallus
Q5ZLD3
629
70952
F97
S
D
Y
F
K
A
M
F
T
G
G
M
K
E
Q
Frog
Xenopus laevis
Q6NRH0
564
63190
T32
S
Q
T
L
C
D
V
T
L
R
V
N
L
K
D
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
T32
S
N
T
L
C
D
I
T
L
R
V
E
G
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
S91
F
A
H
R
V
I
L
S
A
C
S
S
Y
F
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
93.5
90.9
N.A.
60.2
37.2
N.A.
77
22.7
30.9
31.9
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
89
93.7
91.3
N.A.
74.1
51.5
N.A.
80.9
40
45.9
45.1
N.A.
54.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
6.6
13.3
N.A.
93.3
0
0
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
33.3
N.A.
33.3
33.3
N.A.
100
26.6
20
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
10
0
0
19
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
19
0
0
0
10
10
37
0
0
0
10
% C
% Asp:
0
10
0
0
0
19
28
0
0
0
0
0
0
0
19
% D
% Glu:
46
28
28
0
28
0
10
19
0
0
0
10
0
10
0
% E
% Phe:
10
0
0
28
0
0
0
10
0
0
0
0
0
10
10
% F
% Gly:
0
0
0
0
0
10
0
10
0
19
10
0
10
0
0
% G
% His:
0
0
10
10
0
0
0
0
0
0
10
0
19
0
0
% H
% Ile:
10
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
37
19
0
0
0
0
0
0
10
28
0
% K
% Leu:
0
0
0
19
0
0
10
10
19
0
19
0
19
0
0
% L
% Met:
0
0
0
0
0
0
28
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
28
0
0
0
0
19
0
0
10
0
0
28
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
28
10
0
0
0
0
0
0
0
0
0
0
0
28
% Q
% Arg:
0
10
0
10
0
0
0
0
0
19
0
55
0
0
0
% R
% Ser:
37
0
0
0
0
28
0
28
28
37
10
19
0
28
10
% S
% Thr:
0
0
37
0
10
0
0
28
10
0
0
0
28
19
0
% T
% Val:
0
0
0
0
10
10
19
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
19
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _