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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL5 All Species: 22.12
Human Site: S624 Identified Species: 48.67
UniProt: Q96PQ7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PQ7 NP_057074.3 755 84457 S624 D G S S C L K S V E C F D P H
Chimpanzee Pan troglodytes XP_517151 841 93132 S710 D G S S C L K S V E C F D P H
Rhesus Macaque Macaca mulatta XP_001090229 709 79149 S578 D G S S C L K S V E C F D P H
Dog Lupus familis XP_851357 710 80049 S577 D G S S C L K S V E C F D P H
Cat Felis silvestris
Mouse Mus musculus Q9JI74 751 82914 S619 D G S S C L S S M E Y Y D P H
Rat Rattus norvegicus Q8K430 640 69714 V511 Q V N S W T P V A S M L S R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512881 889 97747 S758 D G S S C L K S V E C F D P H
Chicken Gallus gallus Q5ZLD3 629 70952 G500 A P M T T V R G L H C M C T V
Frog Xenopus laevis Q6NRH0 564 63190 I435 G G Y D G L N I L S S V E R Y
Zebra Danio Brachydanio rerio Q5U374 564 62914 I435 G G Y D G L N I L N S V E R Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 V494 R H N K W V A V S P M S T R R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 93.5 90.9 N.A. 60.2 37.2 N.A. 77 22.7 30.9 31.9 N.A. 37 N.A. N.A. N.A.
Protein Similarity: 100 89 93.7 91.3 N.A. 74.1 51.5 N.A. 80.9 40 45.9 45.1 N.A. 54.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 73.3 6.6 N.A. 100 6.6 13.3 13.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 13.3 N.A. 100 33.3 33.3 33.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 55 0 0 0 0 0 55 0 10 0 0 % C
% Asp: 55 0 0 19 0 0 0 0 0 0 0 0 55 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 55 0 0 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0 % F
% Gly: 19 73 0 0 19 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 55 % H
% Ile: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 46 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 73 0 0 28 0 0 10 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 10 0 19 10 0 0 0 % M
% Asn: 0 0 19 0 0 0 19 0 0 10 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 10 0 0 10 0 0 0 55 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 10 0 0 0 0 0 0 37 19 % R
% Ser: 0 0 55 64 0 0 10 55 10 19 19 10 10 0 0 % S
% Thr: 0 0 0 10 10 10 0 0 0 0 0 0 10 10 0 % T
% Val: 0 10 0 0 0 19 0 19 46 0 0 19 0 0 10 % V
% Trp: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 19 0 0 0 0 0 0 0 10 10 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _