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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL5
All Species:
22.73
Human Site:
Y444
Identified Species:
50
UniProt:
Q96PQ7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PQ7
NP_057074.3
755
84457
Y444
L
I
M
E
A
M
K
Y
H
L
L
P
E
R
R
Chimpanzee
Pan troglodytes
XP_517151
841
93132
Y530
L
I
M
E
A
M
K
Y
H
L
L
P
E
R
R
Rhesus Macaque
Macaca mulatta
XP_001090229
709
79149
Y398
L
I
M
E
A
M
K
Y
H
L
L
P
E
R
R
Dog
Lupus familis
XP_851357
710
80049
Y397
L
I
M
E
A
M
K
Y
H
L
L
P
E
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI74
751
82914
Y439
L
I
L
E
A
M
K
Y
H
L
L
P
E
R
R
Rat
Rattus norvegicus
Q8K430
640
69714
G339
P
R
R
C
E
G
A
G
P
V
L
F
A
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512881
889
97747
Y578
L
I
M
E
A
M
K
Y
H
L
L
P
E
R
R
Chicken
Gallus gallus
Q5ZLD3
629
70952
V328
G
V
L
R
Q
Q
L
V
V
S
K
E
L
R
M
Frog
Xenopus laevis
Q6NRH0
564
63190
Q263
L
R
P
E
L
R
S
Q
M
Q
G
P
R
T
R
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
E263
L
R
P
E
L
R
S
E
M
Q
S
P
R
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
E322
R
K
P
T
R
R
G
E
V
L
F
A
V
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
93.5
90.9
N.A.
60.2
37.2
N.A.
77
22.7
30.9
31.9
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
89
93.7
91.3
N.A.
74.1
51.5
N.A.
80.9
40
45.9
45.1
N.A.
54.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
100
6.6
26.6
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
20
26.6
26.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
55
0
10
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
73
10
0
0
19
0
0
0
10
55
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
10
0
0
0
0
10
10
10
0
0
10
0
0
10
19
% G
% His:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% H
% Ile:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
55
0
0
0
10
0
0
0
0
% K
% Leu:
73
0
19
0
19
0
10
0
0
64
64
0
10
0
0
% L
% Met:
0
0
46
0
0
55
0
0
19
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
28
0
0
0
0
0
10
0
0
73
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
10
0
19
0
0
0
0
10
% Q
% Arg:
10
28
10
10
10
28
0
0
0
0
0
0
19
64
64
% R
% Ser:
0
0
0
0
0
0
19
0
0
10
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
19
0
% T
% Val:
0
10
0
0
0
0
0
10
19
10
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _