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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AQP10 All Species: 11.21
Human Site: S293 Identified Species: 22.42
UniProt: Q96PS8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PS8 NP_536354.2 301 31763 S293 S E L E T P A S A Q M L E C K
Chimpanzee Pan troglodytes XP_001151333 301 31771 S293 S E L E T P A S A Q M L E C K
Rhesus Macaque Macaca mulatta XP_001084728 301 31812 S293 S E L E T P A S A Q M L E C K
Dog Lupus familis XP_855114 298 31524 I290 H K A S D L E I P A S A Q C K
Cat Felis silvestris
Mouse Mus musculus Q8R2N1 292 31549 H285 E E N V K L A H M K H K E Q I
Rat Rattus norvegicus P47862 292 31365 H285 A E N V K L A H M K H K E Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512694 292 31482 N285 Q E N V K L A N V K H K E R I
Chicken Gallus gallus XP_001233182 287 30764 D280 G E E N D V Y D K Y E L T N M
Frog Xenopus laevis NP_001082310 297 32015 H289 T E G I N R P H Y E L V Q S S
Zebra Danio Brachydanio rerio NP_001171215 291 31305 K284 D D N S L K D K Y E L N T V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9ATN4 282 29541 T267 L R E I T K S T S F L K S T S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LAI1 275 28728 S264 L K T R P C P S P V S P S V S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 96.6 85.7 N.A. 47.5 48.1 N.A. 46.8 49.5 47.1 49.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 98 90.6 N.A. 60.7 62.1 N.A. 60.7 64.1 61.7 64.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 20 20 N.A. 20 13.3 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 26.6 33.3 N.A. 33.3 13.3 40 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 24.5 N.A. 23.2 N.A. N.A.
Protein Similarity: N.A. 38.2 N.A. 39.5 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 50 0 25 9 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 34 0 % C
% Asp: 9 9 0 0 17 0 9 9 0 0 0 0 0 0 0 % D
% Glu: 9 67 17 25 0 0 9 0 0 17 9 0 50 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 25 0 0 25 0 0 0 0 % H
% Ile: 0 0 0 17 0 0 0 9 0 0 0 0 0 0 25 % I
% Lys: 0 17 0 0 25 17 0 9 9 25 0 34 0 0 34 % K
% Leu: 17 0 25 0 9 34 0 0 0 0 25 34 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 17 0 25 0 0 0 9 % M
% Asn: 0 0 34 9 9 0 0 9 0 0 0 9 0 9 9 % N
% Pro: 0 0 0 0 9 25 17 0 17 0 0 9 0 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 25 0 0 17 17 0 % Q
% Arg: 0 9 0 9 0 9 0 0 0 0 0 0 0 9 0 % R
% Ser: 25 0 0 17 0 0 9 34 9 0 17 0 17 9 25 % S
% Thr: 9 0 9 0 34 0 0 9 0 0 0 0 17 9 0 % T
% Val: 0 0 0 25 0 9 0 0 9 9 0 9 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 17 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _