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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4L
All Species:
19.09
Human Site:
S475
Identified Species:
35
UniProt:
Q96PU5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU5
NP_001138436.1
975
111932
S475
R
A
V
K
D
T
L
S
N
P
Q
S
P
Q
P
Chimpanzee
Pan troglodytes
XP_001140254
911
104904
K475
F
P
V
H
M
R
S
K
T
S
L
N
P
N
D
Rhesus Macaque
Macaca mulatta
XP_001088661
1010
115306
S510
R
A
V
K
D
T
L
S
N
P
Q
S
P
Q
P
Dog
Lupus familis
XP_533393
1027
117927
S527
R
A
V
K
D
T
L
S
N
P
Q
S
P
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI0
1004
115400
S504
R
A
V
K
D
T
L
S
N
P
Q
S
P
Q
P
Rat
Rattus norvegicus
Q62940
887
102376
T469
P
P
G
W
E
E
R
T
H
T
D
G
R
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
N635
A
T
M
Y
S
H
Q
N
I
Q
S
P
P
T
P
Chicken
Gallus gallus
XP_424462
1045
119140
S545
R
A
V
K
D
T
L
S
N
P
Q
S
P
Q
P
Frog
Xenopus laevis
Q2TAS2
751
86306
V353
K
E
Q
Q
P
P
Q
V
V
S
L
C
Q
L
P
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
V367
L
K
E
Q
A
Q
S
V
V
S
P
G
N
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
N514
R
R
N
S
E
E
D
N
A
A
V
P
P
M
E
Honey Bee
Apis mellifera
XP_395191
782
90150
W383
H
N
T
R
T
T
Q
W
E
D
P
R
M
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
K411
Y
F
V
D
H
N
T
K
T
T
T
W
D
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.4
90.8
N.A.
94.3
48
N.A.
43.9
85.6
34.1
34.3
N.A.
47.2
49.4
N.A.
N.A.
Protein Similarity:
100
93.4
93.7
92.2
N.A.
95.6
60
N.A.
54
88.4
49
49.5
N.A.
61.8
61.1
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
13.3
100
6.6
6.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
26.6
100
20
13.3
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
0
0
8
0
0
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
39
0
8
0
0
8
8
0
8
8
8
% D
% Glu:
0
8
8
0
16
16
0
0
8
0
0
0
0
0
8
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
16
0
0
0
% G
% His:
8
0
0
8
8
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
8
0
39
0
0
0
16
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
39
0
0
0
16
0
0
16
0
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
8
8
0
0
8
0
16
39
0
0
8
8
8
8
% N
% Pro:
8
16
0
0
8
8
0
0
0
39
16
16
62
0
70
% P
% Gln:
0
0
8
16
0
8
24
0
0
8
39
0
8
39
0
% Q
% Arg:
47
8
0
8
0
8
8
0
0
0
0
8
8
0
0
% R
% Ser:
0
0
0
8
8
0
16
39
0
24
8
39
0
8
0
% S
% Thr:
0
8
8
0
8
47
8
8
16
16
8
0
0
8
0
% T
% Val:
0
0
54
0
0
0
0
16
16
0
8
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _