KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4L
All Species:
15.45
Human Site:
S538
Identified Species:
28.33
UniProt:
Q96PU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU5
NP_001138436.1
975
111932
S538
K
F
P
V
H
M
R
S
K
T
S
L
N
P
N
Chimpanzee
Pan troglodytes
XP_001140254
911
104904
S530
T
G
P
A
V
P
Y
S
R
E
F
K
Q
K
Y
Rhesus Macaque
Macaca mulatta
XP_001088661
1010
115306
S573
K
F
P
V
H
M
R
S
K
T
S
L
N
P
N
Dog
Lupus familis
XP_533393
1027
117927
S590
K
F
P
V
H
M
R
S
K
A
S
L
N
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI0
1004
115400
S567
K
F
P
V
H
M
R
S
K
A
S
L
N
P
N
Rat
Rattus norvegicus
Q62940
887
102376
D524
R
K
L
K
K
Q
T
D
I
P
N
K
F
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
R818
K
I
P
A
H
L
R
R
K
T
S
L
D
P
I
Chicken
Gallus gallus
XP_424462
1045
119140
M608
S
A
G
I
A
D
M
M
S
A
D
S
Y
A
F
Frog
Xenopus laevis
Q2TAS2
751
86306
E408
S
R
E
E
I
F
E
E
S
Y
R
Q
V
M
K
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
E422
S
R
E
E
I
F
E
E
S
Y
R
Q
V
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
N570
G
R
A
S
P
M
P
N
Q
T
R
R
V
E
D
Honey Bee
Apis mellifera
XP_395191
782
90150
S438
R
N
N
I
L
E
D
S
Y
R
I
I
S
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
E466
V
R
R
K
N
I
F
E
D
A
Y
Q
E
I
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.4
90.8
N.A.
94.3
48
N.A.
43.9
85.6
34.1
34.3
N.A.
47.2
49.4
N.A.
N.A.
Protein Similarity:
100
93.4
93.7
92.2
N.A.
95.6
60
N.A.
54
88.4
49
49.5
N.A.
61.8
61.1
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
0
N.A.
60
0
0
0
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
93.3
13.3
N.A.
73.3
6.6
0
0
N.A.
33.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
16
8
0
0
0
0
31
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
8
8
0
8
0
8
0
8
% D
% Glu:
0
0
16
16
0
8
16
24
0
8
0
0
8
16
0
% E
% Phe:
0
31
0
0
0
16
8
0
0
0
8
0
8
0
8
% F
% Gly:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
16
16
8
0
0
8
0
8
8
0
8
8
% I
% Lys:
39
8
0
16
8
0
0
0
39
0
0
16
0
8
16
% K
% Leu:
0
0
8
0
8
8
0
0
0
0
0
39
0
0
0
% L
% Met:
0
0
0
0
0
39
8
8
0
0
0
0
0
16
16
% M
% Asn:
0
8
8
0
8
0
0
8
0
0
8
0
31
0
31
% N
% Pro:
0
0
47
0
8
8
8
0
0
8
0
0
0
39
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
0
24
8
0
0
% Q
% Arg:
16
31
8
0
0
0
39
8
8
8
24
8
0
0
0
% R
% Ser:
24
0
0
8
0
0
0
47
24
0
39
8
8
8
0
% S
% Thr:
8
0
0
0
0
0
8
0
0
31
0
0
0
0
0
% T
% Val:
8
0
0
31
8
0
0
0
0
0
0
0
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
16
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _