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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4L
All Species:
23.64
Human Site:
Y126
Identified Species:
43.33
UniProt:
Q96PU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU5
NP_001138436.1
975
111932
Y126
D
P
T
M
E
R
P
Y
T
F
K
D
F
L
L
Chimpanzee
Pan troglodytes
XP_001140254
911
104904
Y126
D
P
T
M
E
R
P
Y
T
F
K
D
F
L
L
Rhesus Macaque
Macaca mulatta
XP_001088661
1010
115306
Y157
D
P
T
M
E
R
P
Y
T
F
K
D
F
L
L
Dog
Lupus familis
XP_533393
1027
117927
Y178
D
P
T
M
E
R
P
Y
T
F
K
D
F
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI0
1004
115400
Y154
D
P
T
M
E
R
P
Y
T
F
K
D
F
L
L
Rat
Rattus norvegicus
Q62940
887
102376
N129
K
S
L
N
P
K
W
N
E
E
I
L
F
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
G200
R
T
L
P
R
G
D
G
S
L
A
N
G
I
V
Chicken
Gallus gallus
XP_424462
1045
119140
Y196
D
P
S
M
E
R
P
Y
T
F
K
D
F
L
L
Frog
Xenopus laevis
Q2TAS2
751
86306
T17
G
P
V
K
L
R
L
T
V
L
C
A
K
N
L
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
R31
L
V
K
K
D
F
F
R
L
P
D
P
F
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
E176
Q
E
G
R
T
I
G
E
Q
S
Y
T
L
R
P
Honey Bee
Apis mellifera
XP_395191
782
90150
D47
K
D
I
F
G
A
S
D
P
Y
V
R
V
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
K75
I
Q
V
F
D
Q
K
K
F
K
K
K
D
Q
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.4
90.8
N.A.
94.3
48
N.A.
43.9
85.6
34.1
34.3
N.A.
47.2
49.4
N.A.
N.A.
Protein Similarity:
100
93.4
93.7
92.2
N.A.
95.6
60
N.A.
54
88.4
49
49.5
N.A.
61.8
61.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
93.3
20
6.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
26.6
100
20
13.3
N.A.
0
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
47
8
0
0
16
0
8
8
0
0
8
47
8
8
0
% D
% Glu:
0
8
0
0
47
0
0
8
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
16
0
8
8
0
8
47
0
0
62
0
0
% F
% Gly:
8
0
8
0
8
8
8
8
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
0
0
0
0
8
0
0
8
0
% I
% Lys:
16
0
8
16
0
8
8
8
0
8
54
8
8
0
8
% K
% Leu:
8
0
16
0
8
0
8
0
8
16
0
8
8
47
62
% L
% Met:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
8
0
8
0
% N
% Pro:
0
54
0
8
8
0
47
0
8
8
0
8
0
0
8
% P
% Gln:
8
8
0
0
0
8
0
0
8
0
0
0
0
8
0
% Q
% Arg:
8
0
0
8
8
54
0
8
0
0
0
8
0
16
0
% R
% Ser:
0
8
8
0
0
0
8
0
8
8
0
0
0
0
0
% S
% Thr:
0
8
39
0
8
0
0
8
47
0
0
8
0
0
0
% T
% Val:
0
8
16
0
0
0
0
0
8
0
8
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _