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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4L
All Species:
34.55
Human Site:
Y951
Identified Species:
63.33
UniProt:
Q96PU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU5
NP_001138436.1
975
111932
Y951
N
R
L
D
L
P
P
Y
E
T
F
E
D
L
R
Chimpanzee
Pan troglodytes
XP_001140254
911
104904
Y887
N
R
L
D
L
P
P
Y
E
T
F
E
D
L
R
Rhesus Macaque
Macaca mulatta
XP_001088661
1010
115306
Y986
N
R
L
D
L
P
P
Y
E
T
F
E
D
L
R
Dog
Lupus familis
XP_533393
1027
117927
Y1003
N
R
L
D
L
P
P
Y
E
T
F
E
D
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI0
1004
115400
Y980
N
R
L
D
L
P
P
Y
E
T
F
E
D
L
R
Rat
Rattus norvegicus
Q62940
887
102376
Y863
N
R
L
D
L
P
P
Y
E
S
F
D
E
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
Y1231
N
R
L
D
L
P
P
Y
E
S
F
E
D
L
W
Chicken
Gallus gallus
XP_424462
1045
119140
Y1021
N
R
L
D
L
P
L
Y
E
S
F
D
D
L
R
Frog
Xenopus laevis
Q2TAS2
751
86306
I742
Y
E
K
L
L
T
A
I
E
E
T
C
G
F
A
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
I756
Y
D
K
L
L
T
A
I
E
E
T
C
G
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
Y983
N
R
L
D
L
P
P
Y
E
G
Y
L
Q
L
K
Honey Bee
Apis mellifera
XP_395191
782
90150
E773
E
K
L
I
K
A
I
E
G
S
Q
G
F
A
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
V800
K
Q
K
L
T
L
A
V
E
E
T
I
G
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.4
90.8
N.A.
94.3
48
N.A.
43.9
85.6
34.1
34.3
N.A.
47.2
49.4
N.A.
N.A.
Protein Similarity:
100
93.4
93.7
92.2
N.A.
95.6
60
N.A.
54
88.4
49
49.5
N.A.
61.8
61.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
86.6
80
13.3
13.3
N.A.
66.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
93.3
13.3
13.3
N.A.
80
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
24
0
0
0
0
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
0
8
0
70
0
0
0
0
0
0
0
16
54
0
0
% D
% Glu:
8
8
0
0
0
0
0
8
93
24
0
47
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
62
0
8
24
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
0
8
24
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
16
0
0
0
8
0
0
0
% I
% Lys:
8
8
24
0
8
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
77
24
85
8
8
0
0
0
0
8
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
70
62
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% Q
% Arg:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
47
% R
% Ser:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
16
0
0
0
39
24
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% W
% Tyr:
16
0
0
0
0
0
0
70
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _