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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC85A
All Species:
6.67
Human Site:
Y409
Identified Species:
16.3
UniProt:
Q96PX6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PX6
NP_001073902
553
59966
Y409
S
P
H
H
R
N
V
Y
S
G
M
N
E
S
T
Chimpanzee
Pan troglodytes
XP_525759
553
59969
Y409
S
P
H
H
R
N
V
Y
S
G
M
N
E
S
T
Rhesus Macaque
Macaca mulatta
XP_001115006
391
41845
L261
T
L
S
Y
V
R
Q
L
E
A
R
V
R
Q
L
Dog
Lupus familis
XP_538498
369
40265
P239
E
Q
Q
R
H
P
H
P
G
S
S
P
E
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SP85
500
54465
K358
G
T
S
P
E
H
L
K
Q
H
Y
G
A
S
P
Rat
Rattus norvegicus
XP_002725064
545
59478
M404
H
R
N
V
Y
S
G
M
N
E
S
T
L
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421357
392
44299
S262
E
D
D
N
K
L
L
S
Q
Q
S
S
T
G
D
Frog
Xenopus laevis
Q4V872
390
43971
S260
E
D
D
N
K
L
L
S
Q
H
S
T
S
G
E
Zebra Danio
Brachydanio rerio
Q6DHL7
399
45075
L269
S
R
Y
S
L
S
K
L
S
M
K
Y
N
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193795
394
44088
I264
S
R
N
Y
G
S
S
I
E
N
G
N
R
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
69.8
59.8
N.A.
83.7
92.4
N.A.
N.A.
38.5
39.4
36.8
N.A.
N.A.
N.A.
N.A.
25.8
Protein Similarity:
100
98.7
69.8
61.6
N.A.
85.1
93.6
N.A.
N.A.
52.7
52
50
N.A.
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
100
0
6.6
N.A.
6.6
6.6
N.A.
N.A.
0
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
13.3
N.A.
20
26.6
N.A.
N.A.
26.6
20
26.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
20
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
30
0
0
0
10
0
0
0
20
10
0
0
30
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
10
0
10
20
10
10
0
20
10
% G
% His:
10
0
20
20
10
10
10
0
0
20
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
0
10
10
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
0
10
20
30
20
0
0
0
0
10
0
20
% L
% Met:
0
0
0
0
0
0
0
10
0
10
20
0
0
0
0
% M
% Asn:
0
0
20
20
0
20
0
0
10
10
0
30
10
0
0
% N
% Pro:
0
20
0
10
0
10
0
10
0
0
0
10
0
10
20
% P
% Gln:
0
10
10
0
0
0
10
0
30
10
0
0
0
10
0
% Q
% Arg:
0
30
0
10
20
10
0
0
0
0
10
0
20
0
0
% R
% Ser:
40
0
20
10
0
30
10
20
30
10
40
10
10
40
0
% S
% Thr:
10
10
0
0
0
0
0
0
0
0
0
20
10
10
20
% T
% Val:
0
0
0
10
10
0
20
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
20
10
0
0
20
0
0
10
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _