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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG4B
All Species:
4.55
Human Site:
T34
Identified Species:
12.5
UniProt:
Q96PX9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PX9
NP_443141.3
1271
139667
T34
G
A
S
R
D
L
G
T
G
A
V
A
S
G
T
Chimpanzee
Pan troglodytes
XP_526816
1617
177550
Q380
E
S
L
D
A
C
I
Q
R
T
L
S
A
L
Y
Rhesus Macaque
Macaca mulatta
XP_001087633
1210
132988
D30
F
A
V
C
S
F
R
D
A
W
E
E
E
E
P
Dog
Lupus familis
XP_851955
1405
155809
R166
K
C
L
S
Q
L
G
R
G
S
E
E
V
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UPH7
1517
165114
T159
G
I
N
K
D
R
P
T
G
R
L
S
T
C
L
Rat
Rattus norvegicus
Q63406
1149
129391
A31
D
G
T
S
R
E
E
A
D
H
Q
V
D
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513981
1735
196135
H134
L
Q
V
V
S
V
G
H
Q
S
A
K
L
V
I
Chicken
Gallus gallus
XP_414038
1260
141915
S31
A
C
A
L
E
E
T
S
T
A
V
S
P
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394195
1121
125609
R29
C
A
E
A
D
G
A
R
E
T
S
C
P
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.9
34.7
45.9
N.A.
25.4
24.7
N.A.
41.2
32.9
N.A.
N.A.
N.A.
N.A.
28.2
N.A.
N.A.
Protein Similarity:
100
75.5
49.4
56.8
N.A.
38.9
40.2
N.A.
52.2
49
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
P-Site Identity:
100
0
6.6
20
N.A.
26.6
0
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
6.6
26.6
N.A.
60
13.3
N.A.
20
40
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
34
12
12
12
0
12
12
12
23
12
12
12
12
0
% A
% Cys:
12
23
0
12
0
12
0
0
0
0
0
12
0
12
0
% C
% Asp:
12
0
0
12
34
0
0
12
12
0
0
0
12
0
0
% D
% Glu:
12
0
12
0
12
23
12
0
12
0
23
23
12
23
0
% E
% Phe:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
12
0
0
0
12
34
0
34
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
12
% I
% Lys:
12
0
0
12
0
0
0
0
0
0
0
12
0
0
12
% K
% Leu:
12
0
23
12
0
23
0
0
0
0
23
0
12
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
23
12
12
% P
% Gln:
0
12
0
0
12
0
0
12
12
0
12
0
0
0
0
% Q
% Arg:
0
0
0
12
12
12
12
23
12
12
0
0
0
0
12
% R
% Ser:
0
12
12
23
23
0
0
12
0
23
12
34
12
0
12
% S
% Thr:
0
0
12
0
0
0
12
23
12
23
0
0
12
0
12
% T
% Val:
0
0
23
12
0
12
0
0
0
0
23
12
12
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _