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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FMNL2 All Species: 16.36
Human Site: S537 Identified Species: 40
UniProt: Q96PY5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PY5 NP_443137.2 1086 123321 S537 P P P L P P S S D T P E T V Q
Chimpanzee Pan troglodytes XP_001139667 1087 123399 S537 P P P L P P S S D T P E T V Q
Rhesus Macaque Macaca mulatta XP_001083916 1071 121992 S537 P P P L P L S S D T P E T V Q
Dog Lupus familis XP_533358 1119 127726 P596 P P P P P P P P P P P L P G P
Cat Felis silvestris
Mouse Mus musculus A2APV2 1086 123083 S537 P P P L P P S S D T S E A A Q
Rat Rattus norvegicus XP_002726197 1085 123117 S537 P P P L P P S S D T P E A A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234981 1148 129855 A596 P P P L P A L A A A S E A V Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920583 1042 118401 V526 S A V P V E A V A P P P P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUC6 1183 133140 P627 S A A P P P P P P P A P P A P
Honey Bee Apis mellifera XP_394380 1015 115571 P497 P A P P P P P P P P C P P P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 93.4 75.7 N.A. 94 94.7 N.A. N.A. 85.1 N.A. 69 N.A. 43.2 44.2 N.A. N.A.
Protein Similarity: 100 99.9 93.8 80.3 N.A. 95.4 95.6 N.A. N.A. 88.3 N.A. 82 N.A. 61.9 64 N.A. N.A.
P-Site Identity: 100 100 93.3 40 N.A. 80 86.6 N.A. N.A. 53.3 N.A. 6.6 N.A. 13.3 26.6 N.A. N.A.
P-Site Similarity: 100 100 93.3 40 N.A. 80 86.6 N.A. N.A. 60 N.A. 13.3 N.A. 13.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 30 10 0 0 10 10 10 20 10 10 0 30 30 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 60 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 60 0 10 10 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 80 70 80 40 90 70 30 30 30 40 60 30 40 20 40 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 0 0 0 0 0 50 50 0 0 20 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 50 0 0 30 0 0 % T
% Val: 0 0 10 0 10 0 0 10 0 0 0 0 0 40 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _