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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEK1 All Species: 14.85
Human Site: T506 Identified Species: 27.22
UniProt: Q96PY6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PY6 NP_036356.1 1258 142828 T506 D A D D I R K T L K R L K A V
Chimpanzee Pan troglodytes XP_001153129 1258 142786 T506 D A D D I R K T L K R L K A V
Rhesus Macaque Macaca mulatta XP_001082793 1258 142958 T506 D A D D I R K T L K R L K A V
Dog Lupus familis XP_543184 1286 146207 S506 N A D A F R K S L N R L K I M
Cat Felis silvestris
Mouse Mus musculus P51954 1203 136672 K503 K R E A M Q N K A R A E G H V
Rat Rattus norvegicus NP_001099552 648 74414
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513277 864 98961 S208 R H P F E G N S L H Q L V L K
Chicken Gallus gallus XP_420401 1281 145243 K510 D A D A I R K K V K R L K E V
Frog Xenopus laevis Q7ZZC8 944 104521 P288 A D E I L E R P I L S W R R R
Zebra Danio Brachydanio rerio Q90XC2 697 76523 T41 E I P V E Q M T R D E R L A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782796 1091 120115 D435 G A A M F K E D R S K R Q Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CAU7 606 68016
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48479 858 94329 M202 Y V G T P F Y M S P E I C A A
Conservation
Percent
Protein Identity: 100 99.6 97.5 85 N.A. 79.2 45.9 N.A. 30.2 66.2 22.4 22.7 N.A. N.A. N.A. N.A. 32.9
Protein Similarity: 100 99.7 98.4 90.8 N.A. 85.6 48.5 N.A. 44.3 78 39.2 34.4 N.A. N.A. N.A. N.A. 48.5
P-Site Identity: 100 100 100 53.3 N.A. 6.6 0 N.A. 13.3 73.3 0 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 73.3 N.A. 33.3 0 N.A. 26.6 80 33.3 26.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. 20.1
Protein Similarity: N.A. N.A. N.A. 33.7 N.A. 35.1
P-Site Identity: N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 0 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 47 8 24 0 0 0 0 8 0 8 0 0 39 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 31 8 39 24 0 0 0 8 0 8 0 0 0 0 0 % D
% Glu: 8 0 16 0 16 8 8 0 0 0 16 8 0 8 8 % E
% Phe: 0 0 0 8 16 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 8 0 0 0 8 0 % H
% Ile: 0 8 0 8 31 0 0 0 8 0 0 8 0 8 0 % I
% Lys: 8 0 0 0 0 8 39 16 0 31 8 0 39 0 8 % K
% Leu: 0 0 0 0 8 0 0 0 39 8 0 47 8 8 0 % L
% Met: 0 0 0 8 8 0 8 8 0 0 0 0 0 0 8 % M
% Asn: 8 0 0 0 0 0 16 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 16 0 8 0 0 8 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 16 0 0 0 0 8 0 8 8 0 % Q
% Arg: 8 8 0 0 0 39 8 0 16 8 39 16 8 8 8 % R
% Ser: 0 0 0 0 0 0 0 16 8 8 8 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 31 0 0 0 0 0 0 0 % T
% Val: 0 8 0 8 0 0 0 0 8 0 0 0 8 0 39 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _