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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEK1 All Species: 17.88
Human Site: Y321 Identified Species: 32.78
UniProt: Q96PY6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PY6 NP_036356.1 1258 142828 Y321 K Y G I P L A Y K K Y G D K K
Chimpanzee Pan troglodytes XP_001153129 1258 142786 Y321 K Y G I P L A Y K K Y G D K K
Rhesus Macaque Macaca mulatta XP_001082793 1258 142958 Y321 K Y G I P L T Y K K Y G E K K
Dog Lupus familis XP_543184 1286 146207 Y321 K Y G V P L T Y K K F G D K K
Cat Felis silvestris
Mouse Mus musculus P51954 1203 136672 Y321 K Y G V P L T Y K K Y G D K K
Rat Rattus norvegicus NP_001099552 648 74414
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513277 864 98961 S68 P N I V A F F S S L Q E K N K
Chicken Gallus gallus XP_420401 1281 145243 M321 K Y G V P L A M K K C Y D A P
Frog Xenopus laevis Q7ZZC8 944 104521 C148 Q I V S A V S C I H K A G I L
Zebra Danio Brachydanio rerio Q90XC2 697 76523
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782796 1091 120115 P292 I P K A I S N P A A K Y G P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CAU7 606 68016
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48479 858 94329 R62 F S I L S T L R H P N I V G Y
Conservation
Percent
Protein Identity: 100 99.6 97.5 85 N.A. 79.2 45.9 N.A. 30.2 66.2 22.4 22.7 N.A. N.A. N.A. N.A. 32.9
Protein Similarity: 100 99.7 98.4 90.8 N.A. 85.6 48.5 N.A. 44.3 78 39.2 34.4 N.A. N.A. N.A. N.A. 48.5
P-Site Identity: 100 100 86.6 80 N.A. 86.6 0 N.A. 6.6 60 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 0 N.A. 13.3 66.6 20 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. 20.1
Protein Similarity: N.A. N.A. N.A. 33.7 N.A. 35.1
P-Site Identity: N.A. N.A. N.A. 0 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 0 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 16 0 24 0 8 8 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % E
% Phe: 8 0 0 0 0 8 8 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 47 0 0 0 0 0 0 0 0 39 16 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % H
% Ile: 8 8 16 24 8 0 0 0 8 0 0 8 0 8 0 % I
% Lys: 47 0 8 0 0 0 0 0 47 47 16 0 8 39 47 % K
% Leu: 0 0 0 8 0 47 8 0 0 8 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 0 0 8 0 0 8 0 % N
% Pro: 8 8 0 0 47 0 0 8 0 8 0 0 0 8 8 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 8 8 8 8 8 8 0 0 0 0 0 8 % S
% Thr: 0 0 0 0 0 8 24 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 31 0 8 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 47 0 0 0 0 0 39 0 0 31 16 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _