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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUS7
All Species:
26.97
Human Site:
Y374
Identified Species:
49.44
UniProt:
Q96PZ0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PZ0
NP_061915.2
661
75035
Y374
K
E
I
G
F
I
N
Y
Y
G
M
Q
R
F
G
Chimpanzee
Pan troglodytes
XP_527856
656
74395
Y369
K
E
I
G
F
I
N
Y
Y
G
M
Q
R
F
G
Rhesus Macaque
Macaca mulatta
XP_001089755
661
74868
Y374
R
E
I
G
F
I
N
Y
Y
G
M
Q
R
F
G
Dog
Lupus familis
XP_540388
666
75063
Y379
K
E
I
G
F
I
N
Y
Y
G
M
Q
R
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE46
702
79178
E418
E
R
I
L
E
A
I
E
N
V
K
N
K
G
F
Rat
Rattus norvegicus
XP_001061692
755
84454
Y468
Q
Q
T
G
F
I
N
Y
Y
G
M
Q
R
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508639
669
75642
Y382
R
E
I
G
F
I
N
Y
F
G
M
Q
R
F
G
Chicken
Gallus gallus
XP_415954
650
73974
R368
I
N
Y
Y
G
M
Q
R
F
G
T
T
A
V
P
Frog
Xenopus laevis
NP_001089667
653
74150
Y366
R
D
I
G
F
I
N
Y
Y
G
M
Q
R
F
G
Zebra Danio
Brachydanio rerio
Q1L8I0
643
73094
E364
K
V
I
E
E
A
V
E
N
V
K
N
K
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121511
601
68859
I321
D
L
I
E
A
R
K
I
Y
E
T
T
K
D
A
Nematode Worm
Caenorhab. elegans
Q17426
577
64613
V298
K
R
D
W
E
K
A
V
K
M
I
M
T
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08647
676
76984
D379
E
L
I
L
S
D
Q
D
N
V
L
P
K
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.6
91.1
N.A.
27.7
76.9
N.A.
82.5
80.6
74.7
24
N.A.
N.A.
36.1
25.5
N.A.
Protein Similarity:
100
99.2
99.2
94.7
N.A.
47
82.1
N.A.
89.2
88.9
86.6
41.4
N.A.
N.A.
56.2
45.6
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
6.6
80
N.A.
86.6
6.6
86.6
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
100
20
100
20
N.A.
N.A.
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
16
8
0
0
0
0
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
8
0
8
0
0
0
0
0
8
0
% D
% Glu:
16
39
0
16
24
0
0
16
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
54
0
0
0
16
0
0
0
0
54
16
% F
% Gly:
0
0
0
54
8
0
0
0
0
62
0
0
0
16
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
77
0
0
54
8
8
0
0
8
0
0
0
0
% I
% Lys:
39
0
0
0
0
8
8
0
8
0
16
0
31
0
8
% K
% Leu:
0
16
0
16
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
8
54
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
54
0
24
0
0
16
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% P
% Gln:
8
8
0
0
0
0
16
0
0
0
0
54
0
0
0
% Q
% Arg:
24
16
0
0
0
8
0
8
0
0
0
0
54
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
16
16
8
0
0
% T
% Val:
0
8
0
0
0
0
8
8
0
24
0
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
54
54
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _