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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG1
All Species:
20
Human Site:
S146
Identified Species:
48.89
UniProt:
Q96Q15
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96Q15
NP_055907.3
3657
410261
S146
Y
S
D
E
S
R
L
S
N
L
L
R
R
I
T
Chimpanzee
Pan troglodytes
XP_001152164
3661
410402
S150
Y
S
D
E
S
R
L
S
N
L
L
R
R
I
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851552
3709
415786
S199
Y
S
E
E
S
R
L
S
N
L
L
R
R
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKX6
3658
409724
S148
Y
S
D
E
S
R
L
S
N
L
L
R
R
I
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509568
3636
408206
Q146
R
R
L
A
T
V
K
Q
L
K
E
F
I
Q
Q
Chicken
Gallus gallus
XP_414907
3662
410882
S149
Y
S
D
E
S
R
L
S
N
L
L
R
R
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073513
3640
405042
R157
R
E
D
D
R
E
R
R
L
A
T
M
K
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q70PP2
3218
361568
Honey Bee
Apis mellifera
XP_001122895
3324
377624
T70
D
F
N
A
P
R
G
T
L
V
I
C
P
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788693
3569
398805
F146
T
G
Q
D
L
K
R
F
F
G
W
A
F
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.8
N.A.
97.5
N.A.
N.A.
94.7
93.3
N.A.
73.3
N.A.
25.2
33.1
N.A.
33.9
Protein Similarity:
100
99.6
N.A.
97.6
N.A.
98.8
N.A.
N.A.
97.5
97.3
N.A.
85.6
N.A.
43.7
53.3
N.A.
53.8
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
N.A.
N.A.
0
100
N.A.
6.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
6.6
100
N.A.
20
N.A.
0
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
50
20
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
10
50
0
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
10
10
0
0
10
10
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
10
50
0
% I
% Lys:
0
0
0
0
0
10
10
0
0
10
0
0
10
0
10
% K
% Leu:
0
0
10
0
10
0
50
0
30
50
50
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
10
0
0
0
0
0
50
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
0
0
0
20
10
% Q
% Arg:
20
10
0
0
10
60
20
10
0
0
0
50
50
10
0
% R
% Ser:
0
50
0
0
50
0
0
50
0
0
0
0
0
0
10
% S
% Thr:
10
0
0
0
10
0
0
10
0
0
10
0
0
10
50
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _