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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMG1 All Species: 29.09
Human Site: S3342 Identified Species: 71.11
UniProt: Q96Q15 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96Q15 NP_055907.3 3657 410261 S3342 F A S Q F N S S V S E L E L R
Chimpanzee Pan troglodytes XP_001152164 3661 410402 S3346 F A S Q F N S S V S E L E L R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851552 3709 415786 S3394 F A S Q F N S S V S E L E L R
Cat Felis silvestris
Mouse Mus musculus Q8BKX6 3658 409724 S3343 F A S Q F N S S V S E L E L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509568 3636 408206 S3321 F A S Q F N S S V S E L E L R
Chicken Gallus gallus XP_414907 3662 410882 S3347 F A S Q F N S S V S E L E L R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073513 3640 405042 S3328 Y A A Q F N T S V S S L E L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q70PP2 3218 361568 Q2927 M S H V A L L Q K M T D G A G
Honey Bee Apis mellifera XP_001122895 3324 377624 T3032 L S S C E K L T R Q H N L A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788693 3569 398805 S3275 P A R S A I M S D M R K R L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 96.8 N.A. 97.5 N.A. N.A. 94.7 93.3 N.A. 73.3 N.A. 25.2 33.1 N.A. 33.9
Protein Similarity: 100 99.6 N.A. 97.6 N.A. 98.8 N.A. N.A. 97.5 97.3 N.A. 85.6 N.A. 43.7 53.3 N.A. 53.8
P-Site Identity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 100 100 N.A. 66.6 N.A. 0 6.6 N.A. 20
P-Site Similarity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 100 100 N.A. 93.3 N.A. 6.6 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 80 10 0 20 0 0 0 0 0 0 0 0 20 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 60 0 70 0 0 % E
% Phe: 60 0 0 0 70 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 0 % K
% Leu: 10 0 0 0 0 10 20 0 0 0 0 70 10 80 0 % L
% Met: 10 0 0 0 0 0 10 0 0 20 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 70 0 0 0 0 0 10 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 70 0 0 0 10 0 10 0 0 0 0 20 % Q
% Arg: 0 0 10 0 0 0 0 0 10 0 10 0 10 0 60 % R
% Ser: 0 20 70 10 0 0 60 80 0 70 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 10 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 70 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _