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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMG1 All Species: 18.79
Human Site: T3518 Identified Species: 45.93
UniProt: Q96Q15 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96Q15 NP_055907.3 3657 410261 T3518 S P L V T D A T N E C S S P T
Chimpanzee Pan troglodytes XP_001152164 3661 410402 T3522 S P L V T D A T N E C S S P T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851552 3709 415786 T3570 S P L V T D A T N E C S S P T
Cat Felis silvestris
Mouse Mus musculus Q8BKX6 3658 409724 A3519 S P L V T D A A N E C S S P T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509568 3636 408206 T3497 S P L V T D A T N E C S S P T
Chicken Gallus gallus XP_414907 3662 410882 S3523 S P L V T D T S N E C S S P T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073513 3640 405042 G3504 S P L V T E R G S D C I S P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q70PP2 3218 361568 M3086 G L M Q S L Y M R L Q E L R K
Honey Bee Apis mellifera XP_001122895 3324 377624 T3191 L S S Y R S F T E S I S A I V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788693 3569 398805 Q3434 R K K V T E C Q G K A A E A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 96.8 N.A. 97.5 N.A. N.A. 94.7 93.3 N.A. 73.3 N.A. 25.2 33.1 N.A. 33.9
Protein Similarity: 100 99.6 N.A. 97.6 N.A. 98.8 N.A. N.A. 97.5 97.3 N.A. 85.6 N.A. 43.7 53.3 N.A. 53.8
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 N.A. N.A. 100 86.6 N.A. 60 N.A. 0 13.3 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 N.A. N.A. 100 93.3 N.A. 80 N.A. 13.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 50 10 0 0 10 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 70 0 0 0 0 % C
% Asp: 0 0 0 0 0 60 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 20 0 0 10 60 0 10 10 0 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 10 0 10 0 % I
% Lys: 0 10 10 0 0 0 0 0 0 10 0 0 0 0 10 % K
% Leu: 10 10 70 0 0 10 0 0 0 10 0 0 10 0 0 % L
% Met: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 % N
% Pro: 0 70 0 0 0 0 0 0 0 0 0 0 0 70 0 % P
% Gln: 0 0 0 10 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 10 0 0 0 10 0 10 0 10 0 0 0 0 10 0 % R
% Ser: 70 10 10 0 10 10 0 10 10 10 0 70 70 0 0 % S
% Thr: 0 0 0 0 80 0 10 50 0 0 0 0 0 0 70 % T
% Val: 0 0 0 80 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _