KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG1
All Species:
20
Human Site:
Y1577
Identified Species:
48.89
UniProt:
Q96Q15
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96Q15
NP_055907.3
3657
410261
Y1577
V
N
T
M
E
E
E
Y
P
R
I
E
S
E
S
Chimpanzee
Pan troglodytes
XP_001152164
3661
410402
Y1581
V
N
T
M
E
E
E
Y
P
R
I
E
S
E
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851552
3709
415786
Y1629
V
N
T
M
E
E
E
Y
P
R
I
E
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKX6
3658
409724
H1579
A
N
T
V
G
E
E
H
P
R
I
E
S
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509568
3636
408206
Y1556
V
N
T
T
E
E
E
Y
P
R
I
E
S
E
S
Chicken
Gallus gallus
XP_414907
3662
410882
Y1582
V
N
T
L
E
E
E
Y
P
R
I
E
S
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073513
3640
405042
T1565
Q
G
M
P
H
I
T
T
E
T
T
V
S
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q70PP2
3218
361568
S1323
G
E
I
A
A
L
F
S
L
E
Q
G
V
Q
T
Honey Bee
Apis mellifera
XP_001122895
3324
377624
I1428
P
T
T
S
S
I
P
I
S
D
M
I
I
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788693
3569
398805
Y1580
Q
G
H
G
L
A
A
Y
G
V
R
E
A
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.8
N.A.
97.5
N.A.
N.A.
94.7
93.3
N.A.
73.3
N.A.
25.2
33.1
N.A.
33.9
Protein Similarity:
100
99.6
N.A.
97.6
N.A.
98.8
N.A.
N.A.
97.5
97.3
N.A.
85.6
N.A.
43.7
53.3
N.A.
53.8
P-Site Identity:
100
100
N.A.
100
N.A.
73.3
N.A.
N.A.
93.3
93.3
N.A.
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
N.A.
N.A.
93.3
100
N.A.
6.6
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
10
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
0
10
0
0
50
60
60
0
10
10
0
70
0
60
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
20
0
10
10
0
0
0
10
0
0
10
0
10
10
% G
% His:
0
0
10
0
10
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
20
0
10
0
0
60
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
10
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
10
30
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
0
0
10
0
60
0
0
0
0
0
0
% P
% Gln:
20
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
60
10
0
0
0
10
% R
% Ser:
0
0
0
10
10
0
0
10
10
0
0
0
70
0
60
% S
% Thr:
0
10
70
10
0
0
10
10
0
10
10
0
0
0
10
% T
% Val:
50
0
0
10
0
0
0
0
0
10
0
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _