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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALS2
All Species:
22.42
Human Site:
S1226
Identified Species:
54.81
UniProt:
Q96Q42
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96Q42
NP_001129217.1
1657
183666
S1226
T
I
Y
E
G
E
F
S
D
D
W
T
L
S
G
Chimpanzee
Pan troglodytes
Q5BIW4
1657
183718
S1226
T
I
Y
E
G
E
F
S
D
D
W
T
L
S
G
Rhesus Macaque
Macaca mulatta
XP_001091562
1670
184507
I1229
T
M
P
N
G
D
Y
I
E
G
Y
F
S
G
E
Dog
Lupus familis
XP_536032
1656
183433
S1225
T
I
Y
E
G
E
F
S
D
D
W
T
L
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q920R0
1651
182536
S1220
T
I
Y
E
G
E
F
S
D
D
W
T
L
S
G
Rat
Rattus norvegicus
P0C5Y8
1651
182430
S1220
T
I
Y
E
G
E
F
S
D
D
W
T
L
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517899
881
100290
W514
A
V
A
A
D
E
K
W
T
A
V
F
E
E
C
Chicken
Gallus gallus
XP_421940
1649
182052
S1218
T
V
Y
E
G
E
F
S
D
N
W
T
L
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396645
1382
156375
E1015
N
M
N
G
S
W
N
E
G
V
K
V
I
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194321
836
93340
L469
I
F
G
Q
C
R
T
L
L
G
F
V
D
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.5
95.1
N.A.
91.9
91.5
N.A.
46.3
80.1
N.A.
N.A.
N.A.
N.A.
29.6
N.A.
20.8
Protein Similarity:
100
99.9
97.5
97.8
N.A.
95.8
95.1
N.A.
49.9
87.2
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
31.9
P-Site Identity:
100
100
13.3
100
N.A.
100
93.3
N.A.
6.6
86.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
46.6
100
N.A.
100
93.3
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% C
% Asp:
0
0
0
0
10
10
0
0
60
50
0
0
10
0
0
% D
% Glu:
0
0
0
60
0
70
0
10
10
0
0
0
10
10
10
% E
% Phe:
0
10
0
0
0
0
60
0
0
0
10
20
0
10
0
% F
% Gly:
0
0
10
10
70
0
0
0
10
20
0
0
0
10
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
50
0
0
0
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
10
0
0
0
60
0
0
% L
% Met:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
10
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
60
0
0
0
0
10
50
0
% S
% Thr:
70
0
0
0
0
0
10
0
10
0
0
60
0
0
20
% T
% Val:
0
20
0
0
0
0
0
0
0
10
10
20
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
10
0
0
60
0
0
0
0
% W
% Tyr:
0
0
60
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _