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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALS2
All Species:
23.64
Human Site:
S578
Identified Species:
57.78
UniProt:
Q96Q42
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96Q42
NP_001129217.1
1657
183666
S578
S
L
A
L
T
A
K
S
Q
V
Y
S
W
G
S
Chimpanzee
Pan troglodytes
Q5BIW4
1657
183718
S578
S
L
A
L
T
A
K
S
Q
V
Y
S
W
G
S
Rhesus Macaque
Macaca mulatta
XP_001091562
1670
184507
S578
S
L
A
L
T
A
K
S
Q
V
Y
S
W
G
S
Dog
Lupus familis
XP_536032
1656
183433
S577
S
L
A
L
T
A
K
S
Q
V
Y
S
W
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q920R0
1651
182536
S572
S
L
A
L
T
A
K
S
Q
V
Y
S
W
G
S
Rat
Rattus norvegicus
P0C5Y8
1651
182430
S572
S
L
A
L
T
A
K
S
Q
V
Y
S
W
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517899
881
100290
Chicken
Gallus gallus
XP_421940
1649
182052
T570
G
H
H
S
L
A
L
T
A
K
S
Q
V
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396645
1382
156375
L397
L
K
P
A
T
T
S
L
A
L
S
L
R
C
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194321
836
93340
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.5
95.1
N.A.
91.9
91.5
N.A.
46.3
80.1
N.A.
N.A.
N.A.
N.A.
29.6
N.A.
20.8
Protein Similarity:
100
99.9
97.5
97.8
N.A.
95.8
95.1
N.A.
49.9
87.2
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
31.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
10
0
70
0
0
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
60
0
0
10
0
0
0
0
0
% K
% Leu:
10
60
0
60
10
0
10
10
0
10
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
60
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
60
0
0
10
0
0
10
60
0
0
20
60
0
0
70
% S
% Thr:
0
0
0
0
70
10
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
60
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
60
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _