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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALS2CR4 All Species: 16.97
Human Site: S416 Identified Species: 41.48
UniProt: Q96Q45 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96Q45 NP_001037850.1 432 48244 S416 S E E L M F S S E V E E Y P D
Chimpanzee Pan troglodytes XP_001156617 480 52987 S464 S E E L M F S S E V E E Y P D
Rhesus Macaque Macaca mulatta XP_001099517 400 44616 S384 S E E L M F S S E V E E Y P D
Dog Lupus familis XP_545597 410 45490 S394 S E E L M F C S D V E G Y P D
Cat Felis silvestris
Mouse Mus musculus Q3V0J1 427 47324 E407 R P G M D L S E E L M F F S D
Rat Rattus norvegicus NP_001101690 292 32816 F277 L S E E L M F F S D V D E Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519885 276 30366 E261 E E L M F S S E L Q E Y P E L
Chicken Gallus gallus XP_421939 465 51361 T449 S E E L M F H T E I E E F P Q
Frog Xenopus laevis NP_001108263 389 43827 P373 S E E A M F I P E E E D Y P D
Zebra Danio Brachydanio rerio NP_001004636 413 45951 M398 T E A F L M S M E M E Y P N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 90.5 80 N.A. 73.8 57.8 N.A. 47.2 60.8 54.1 48.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 86 91.9 85.4 N.A. 80.3 63.4 N.A. 53.7 73.7 65.9 64.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 20 6.6 N.A. 20 66.6 66.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 40 20 N.A. 26.6 86.6 73.3 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 10 10 0 20 0 0 60 % D
% Glu: 10 80 70 10 0 0 0 20 70 10 80 40 10 10 0 % E
% Phe: 0 0 0 10 10 60 10 10 0 0 0 10 20 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 50 20 10 0 0 10 10 0 0 0 0 10 % L
% Met: 0 0 0 20 60 20 0 10 0 10 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 10 0 0 0 0 0 10 0 0 0 0 20 60 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 60 10 0 0 0 10 60 40 10 0 0 0 0 10 10 % S
% Thr: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 40 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 20 50 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _