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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIB3 All Species: 31.21
Human Site: Y46 Identified Species: 52.82
UniProt: Q96Q77 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96Q77 NP_473454.1 187 21802 Y46 P Q L V P L D Y T T C P D V K
Chimpanzee Pan troglodytes XP_512464 187 21855 Y46 P Q L V P L D Y T T C P D V K
Rhesus Macaque Macaca mulatta XP_001112625 187 21884 Y46 P Q L V P L D Y T T C P D V K
Dog Lupus familis XP_852821 217 25183 Y46 P Q L V P L D Y T S C P D V K
Cat Felis silvestris
Mouse Mus musculus Q9Z309 187 21685 Y46 P N L V P M D Y R K S P I V H
Rat Rattus norvegicus Q568Z7 187 21653 Y46 P N L V P M D Y R K S P I V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510397 225 26316 Y84 P Q L V P L D Y T D Q P E V K
Chicken Gallus gallus XP_418267 187 21871 Y46 P Q L V P L D Y T D K P N V T
Frog Xenopus laevis Q91614 190 21906 T46 P S G Q L D A T G F Q K I Y K
Zebra Danio Brachydanio rerio NP_957000 187 21740 Y46 P H L V P M D Y T N D P D V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24214 170 19248 L38 D L D N S G A L S V D E F M S
Honey Bee Apis mellifera XP_623978 200 23103 S46 N P G T V P R S M T P Q Q A S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25296 175 19620 K43 D S S G S I D K N E F M S I P
Red Bread Mold Neurospora crassa P87072 174 19751 E42 K D N S G T I E R E E F L S L
Conservation
Percent
Protein Identity: 100 99.4 98.4 83.4 N.A. 60.9 60.9 N.A. 64 82.8 25.7 70 N.A. 28.8 49 N.A. N.A.
Protein Similarity: 100 99.4 99.4 83.8 N.A. 79.6 79.6 N.A. 71.5 92.5 43.1 83.9 N.A. 48.1 66.5 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 53.3 53.3 N.A. 80 73.3 13.3 73.3 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 60 60 N.A. 86.6 80 13.3 80 N.A. 13.3 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.9 26.7
Protein Similarity: N.A. N.A. N.A. N.A. 46.5 45.4
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 15 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 29 0 0 0 0 % C
% Asp: 15 8 8 0 0 8 72 0 0 15 15 0 36 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 15 8 8 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 8 8 8 0 0 % F
% Gly: 0 0 15 8 8 8 0 0 8 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 15 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 0 0 22 8 0 % I
% Lys: 8 0 0 0 0 0 0 8 0 15 8 8 0 0 50 % K
% Leu: 0 8 65 0 8 43 0 8 0 0 0 0 8 0 8 % L
% Met: 0 0 0 0 0 22 0 0 8 0 0 8 0 8 0 % M
% Asn: 8 15 8 8 0 0 0 0 8 8 0 0 8 0 0 % N
% Pro: 72 8 0 0 65 8 0 0 0 0 8 65 0 0 8 % P
% Gln: 0 43 0 8 0 0 0 0 0 0 15 8 8 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 22 0 0 0 0 0 0 % R
% Ser: 0 15 8 8 15 0 0 8 8 8 15 0 8 8 15 % S
% Thr: 0 0 0 8 0 8 0 8 50 29 0 0 0 0 8 % T
% Val: 0 0 0 65 8 0 0 0 0 8 0 0 0 65 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 65 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _