Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DERL3 All Species: 44.85
Human Site: S133 Identified Species: 65.78
UniProt: Q96Q80 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96Q80 NP_001002862.1 235 26679 S133 A M L V Y V W S R R S P R V R
Chimpanzee Pan troglodytes XP_001169907 235 26667 S133 A M L V Y V W S R R S P R V R
Rhesus Macaque Macaca mulatta XP_001085558 235 26695 S133 A M L V Y V W S R R S P R V R
Dog Lupus familis XP_543532 420 47546 S322 V M L V Y V W S R R N P R V R
Cat Felis silvestris
Mouse Mus musculus Q9D8K3 228 25959 S133 A M L V Y V W S R R S P H V R
Rat Rattus norvegicus NP_001103047 228 26063 S133 A M L V Y V W S R R S P H V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507159 211 24620 Q124 F F G L L N F Q A P F L P W V
Chicken Gallus gallus XP_415746 239 27598 S133 I M L V Y V W S R R N P Y V R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001331593 247 28512 S132 I M L V Y V W S R R N P F V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQ57 245 28238 C133 L A I T Y I W C Q L N K D V T
Honey Bee Apis mellifera XP_397412 238 27920 S133 I M L V Y V W S R R N P F V R
Nematode Worm Caenorhab. elegans Q21997 237 28015 S131 I M L V Y I W S R R N P M I Q
Sea Urchin Strong. purpuratus XP_786599 252 29483 S133 I M L V Y V W S R R N P Y I R
Poplar Tree Populus trichocarpa
Maize Zea mays Q4G2J4 249 28488 S143 F M M V Y V W S K H N P F I H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZS88 244 28080 N132 A K I I F L S N S L T F M M V
Baker's Yeast Sacchar. cerevisiae Q12743 341 38112 C157 L T S G F I S C I T Y T W S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 98.3 50.9 N.A. 88 88 N.A. 73.6 74 N.A. 71.2 N.A. 29.7 62.1 57.3 62.3
Protein Similarity: 100 100 98.7 52.6 N.A. 89.7 90.6 N.A. 80.8 84 N.A. 81.3 N.A. 50.6 76.8 70 75.4
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 0 80 N.A. 80 N.A. 20 80 60 73.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 13.3 86.6 N.A. 86.6 N.A. 46.6 86.6 86.6 86.6
Percent
Protein Identity: N.A. 45.7 N.A. 45.4 21.4 N.A.
Protein Similarity: N.A. 63.4 N.A. 65.5 35.7 N.A.
P-Site Identity: N.A. 46.6 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 73.3 N.A. 53.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 13 7 0 0 13 0 7 0 0 0 7 7 19 0 0 % F
% Gly: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 13 0 7 % H
% Ile: 32 0 13 7 0 19 0 0 7 0 0 0 0 19 7 % I
% Lys: 0 7 0 0 0 0 0 0 7 0 0 7 0 0 0 % K
% Leu: 13 0 69 7 7 7 0 0 0 13 0 7 0 0 0 % L
% Met: 0 75 7 0 0 0 0 0 0 0 0 0 13 7 0 % M
% Asn: 0 0 0 0 0 7 0 7 0 0 50 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 75 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 0 69 69 0 0 25 0 63 % R
% Ser: 0 0 7 0 0 0 13 75 7 0 32 0 0 7 0 % S
% Thr: 0 7 0 7 0 0 0 0 0 7 7 7 0 0 7 % T
% Val: 7 0 0 75 0 69 0 0 0 0 0 0 0 63 13 % V
% Trp: 0 0 0 0 0 0 82 0 0 0 0 0 7 7 0 % W
% Tyr: 0 0 0 0 82 0 0 0 0 0 7 0 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _