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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DERL3
All Species:
20.61
Human Site:
S136
Identified Species:
30.22
UniProt:
Q96Q80
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96Q80
NP_001002862.1
235
26679
S136
V
Y
V
W
S
R
R
S
P
R
V
R
V
N
F
Chimpanzee
Pan troglodytes
XP_001169907
235
26667
S136
V
Y
V
W
S
R
R
S
P
R
V
R
V
N
F
Rhesus Macaque
Macaca mulatta
XP_001085558
235
26695
S136
V
Y
V
W
S
R
R
S
P
R
V
R
V
N
F
Dog
Lupus familis
XP_543532
420
47546
N325
V
Y
V
W
S
R
R
N
P
R
V
R
V
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8K3
228
25959
S136
V
Y
V
W
S
R
R
S
P
H
V
R
V
N
F
Rat
Rattus norvegicus
NP_001103047
228
26063
S136
V
Y
V
W
S
R
R
S
P
H
V
R
V
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507159
211
24620
F127
L
L
N
F
Q
A
P
F
L
P
W
V
L
M
G
Chicken
Gallus gallus
XP_415746
239
27598
N136
V
Y
V
W
S
R
R
N
P
Y
V
R
M
N
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001331593
247
28512
N135
V
Y
V
W
S
R
R
N
P
F
V
R
M
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQ57
245
28238
N136
T
Y
I
W
C
Q
L
N
K
D
V
T
V
S
F
Honey Bee
Apis mellifera
XP_397412
238
27920
N136
V
Y
V
W
S
R
R
N
P
F
V
R
L
N
F
Nematode Worm
Caenorhab. elegans
Q21997
237
28015
N134
V
Y
I
W
S
R
R
N
P
M
I
Q
M
N
F
Sea Urchin
Strong. purpuratus
XP_786599
252
29483
N136
V
Y
V
W
S
R
R
N
P
Y
I
R
M
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q4G2J4
249
28488
N146
V
Y
V
W
S
K
H
N
P
F
I
H
M
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZS88
244
28080
T135
I
F
L
S
N
S
L
T
F
M
M
V
Y
V
W
Baker's Yeast
Sacchar. cerevisiae
Q12743
341
38112
Y160
G
F
I
S
C
I
T
Y
T
W
S
I
D
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.3
50.9
N.A.
88
88
N.A.
73.6
74
N.A.
71.2
N.A.
29.7
62.1
57.3
62.3
Protein Similarity:
100
100
98.7
52.6
N.A.
89.7
90.6
N.A.
80.8
84
N.A.
81.3
N.A.
50.6
76.8
70
75.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
80
N.A.
80
N.A.
33.3
80
60
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
93.3
N.A.
93.3
N.A.
60
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
45.7
N.A.
45.4
21.4
N.A.
Protein Similarity:
N.A.
63.4
N.A.
65.5
35.7
N.A.
P-Site Identity:
N.A.
46.6
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
80
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
7
0
0
0
7
7
19
0
0
0
0
82
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
7
0
0
13
0
7
0
0
0
% H
% Ile:
7
0
19
0
0
7
0
0
0
0
19
7
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% K
% Leu:
7
7
7
0
0
0
13
0
7
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
13
7
0
32
7
0
% M
% Asn:
0
0
7
0
7
0
0
50
0
0
0
0
0
75
0
% N
% Pro:
0
0
0
0
0
0
7
0
75
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
69
69
0
0
25
0
63
0
0
0
% R
% Ser:
0
0
0
13
75
7
0
32
0
0
7
0
0
13
0
% S
% Thr:
7
0
0
0
0
0
7
7
7
0
0
7
0
0
0
% T
% Val:
75
0
69
0
0
0
0
0
0
0
63
13
44
7
0
% V
% Trp:
0
0
0
82
0
0
0
0
0
7
7
0
0
0
7
% W
% Tyr:
0
82
0
0
0
0
0
7
0
13
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _