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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DERL3
All Species:
34.85
Human Site:
Y218
Identified Species:
51.11
UniProt:
Q96Q80
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96Q80
NP_001002862.1
235
26679
Y218
A
P
A
E
D
P
N
Y
L
P
L
P
E
E
Q
Chimpanzee
Pan troglodytes
XP_001169907
235
26667
Y218
A
P
A
E
D
P
N
Y
L
P
L
P
E
E
Q
Rhesus Macaque
Macaca mulatta
XP_001085558
235
26695
Y218
A
P
A
E
D
P
N
Y
L
P
L
P
E
E
Q
Dog
Lupus familis
XP_543532
420
47546
Y407
A
P
Q
E
D
P
N
Y
L
P
L
P
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8K3
228
25959
Y218
D
P
Q
E
D
P
D
Y
L
P
L
P
E
E
Q
Rat
Rattus norvegicus
NP_001103047
228
26063
Y218
D
P
Q
E
D
P
N
Y
L
P
L
P
E
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507159
211
24620
P204
E
D
G
P
E
P
G
P
A
Q
R
P
P
R
Q
Chicken
Gallus gallus
XP_415746
239
27598
Y218
T
P
E
D
D
P
N
Y
N
P
L
P
E
E
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001331593
247
28512
Y217
P
P
Q
E
D
P
N
Y
A
P
L
P
E
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQ57
245
28238
F218
V
S
G
G
F
G
G
F
G
L
P
P
E
S
R
Honey Bee
Apis mellifera
XP_397412
238
27920
Y218
A
H
P
E
D
P
D
Y
T
P
P
P
E
D
R
Nematode Worm
Caenorhab. elegans
Q21997
237
28015
G222
L
P
E
D
E
R
P
G
G
F
E
W
G
D
E
Sea Urchin
Strong. purpuratus
XP_786599
252
29483
Y218
T
A
P
E
D
P
N
Y
N
P
L
P
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q4G2J4
249
28488
A231
V
V
A
Q
P
P
N
A
G
I
G
A
G
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZS88
244
28080
F233
A
R
P
E
D
V
R
F
A
A
A
P
F
D
E
Baker's Yeast
Sacchar. cerevisiae
Q12743
341
38112
G317
S
G
S
Q
L
R
S
G
P
S
N
L
N
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.3
50.9
N.A.
88
88
N.A.
73.6
74
N.A.
71.2
N.A.
29.7
62.1
57.3
62.3
Protein Similarity:
100
100
98.7
52.6
N.A.
89.7
90.6
N.A.
80.8
84
N.A.
81.3
N.A.
50.6
76.8
70
75.4
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
20
66.6
N.A.
73.3
N.A.
13.3
53.3
6.6
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
26.6
80
N.A.
80
N.A.
26.6
73.3
33.3
73.3
Percent
Protein Identity:
N.A.
45.7
N.A.
45.4
21.4
N.A.
Protein Similarity:
N.A.
63.4
N.A.
65.5
35.7
N.A.
P-Site Identity:
N.A.
20
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
7
25
0
0
0
0
7
19
7
7
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
7
0
13
69
0
13
0
0
0
0
0
0
25
0
% D
% Glu:
7
0
13
63
13
0
0
0
0
0
7
0
69
50
19
% E
% Phe:
0
0
0
0
7
0
0
13
0
7
0
0
7
0
7
% F
% Gly:
0
7
13
7
0
7
13
13
19
0
7
0
13
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
7
0
0
0
38
7
57
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
57
0
13
0
7
0
7
0
0
% N
% Pro:
7
57
19
7
7
75
7
7
7
63
13
82
7
0
0
% P
% Gln:
0
0
25
13
0
0
0
0
0
7
0
0
0
7
44
% Q
% Arg:
0
7
0
0
0
13
7
0
0
0
7
0
0
7
25
% R
% Ser:
7
7
7
0
0
0
7
0
0
7
0
0
0
7
0
% S
% Thr:
13
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% T
% Val:
13
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
63
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _