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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSDMA
All Species:
19.7
Human Site:
T259
Identified Species:
61.9
UniProt:
Q96QA5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QA5
NP_835465.2
445
49379
T259
D
V
H
E
G
F
R
T
L
K
E
E
V
Q
R
Chimpanzee
Pan troglodytes
XP_001171203
445
49374
T259
D
V
H
E
G
F
R
T
L
K
E
E
V
Q
R
Rhesus Macaque
Macaca mulatta
XP_001094878
449
49807
T263
D
V
H
E
G
F
G
T
L
K
E
E
V
Q
R
Dog
Lupus familis
XP_850338
442
49582
T256
E
E
H
E
N
F
K
T
L
K
E
E
V
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EST1
446
49575
T260
E
M
H
E
D
F
K
T
L
K
E
E
V
Q
R
Rat
Rattus norvegicus
P85967
474
53233
Y284
P
V
H
L
D
F
K
Y
L
E
K
E
V
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505287
446
48775
A260
E
V
P
E
D
F
G
A
L
Q
E
E
V
E
S
Chicken
Gallus gallus
NP_001026532
452
49940
A253
F
A
H
T
E
V
E
A
L
E
E
E
V
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.8
84.9
N.A.
88.3
31.2
N.A.
66.3
32.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
96.4
91
N.A.
94.1
48.5
N.A.
80
52.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
40
N.A.
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
60
N.A.
66.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
0
25
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
38
0
0
0
38
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
38
13
0
75
13
0
13
0
0
25
88
100
0
13
13
% E
% Phe:
13
0
0
0
0
88
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
38
0
25
0
0
0
0
0
0
0
0
% G
% His:
0
0
88
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
38
0
0
63
13
0
0
13
0
% K
% Leu:
0
0
0
13
0
0
0
0
100
0
0
0
0
0
13
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
0
0
0
63
0
% Q
% Arg:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
63
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% S
% Thr:
0
0
0
13
0
0
0
63
0
0
0
0
0
0
0
% T
% Val:
0
63
0
0
0
13
0
0
0
0
0
0
100
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _