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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLC1 All Species: 10.3
Human Site: S380 Identified Species: 28.33
UniProt: Q96QB1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QB1 NP_006085.2 1528 170592 S380 L S T S S S P S G T P T N L R
Chimpanzee Pan troglodytes XP_001138622 1528 170386 S380 L S T S S S P S G T P T N L R
Rhesus Macaque Macaca mulatta XP_001091659 1528 170709 S380 L S T S S S P S G T P M N L R
Dog Lupus familis XP_849359 1004 111320
Cat Felis silvestris
Mouse Mus musculus Q9R0Z9 1092 123349 E18 L T Q I E A K E A C D W L R V
Rat Rattus norvegicus Q63744 1091 123396 A16 M I L T Q I E A K E A C D W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511069 1089 120124 A15 H G C R V H P A F S L R V E N
Chicken Gallus gallus XP_420693 1575 176028 S424 E N A L S A G S S P S S T P T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921774 1100 122120 A26 A C T W L R A A G F P Q Y A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.3 38.6 N.A. 66.2 66.3 N.A. 38.9 72.8 N.A. 41.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.3 98.4 50 N.A. 68 68.1 N.A. 51.1 81.9 N.A. 53 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 0 N.A. 6.6 0 N.A. 6.6 13.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 0 N.A. 20 26.6 N.A. 20 33.3 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 0 0 23 12 34 12 0 12 0 0 12 0 % A
% Cys: 0 12 12 0 0 0 0 0 0 12 0 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 12 0 12 0 0 % D
% Glu: 12 0 0 0 12 0 12 12 0 12 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 % F
% Gly: 0 12 0 0 0 0 12 0 45 0 0 0 0 0 0 % G
% His: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 12 0 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 12 0 12 0 0 0 0 0 0 % K
% Leu: 45 0 12 12 12 0 0 0 0 0 12 0 12 34 12 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 0 0 0 34 0 12 % N
% Pro: 0 0 0 0 0 0 45 0 0 12 45 0 0 12 0 % P
% Gln: 0 0 12 0 12 0 0 0 0 0 0 12 0 0 12 % Q
% Arg: 0 0 0 12 0 12 0 0 0 0 0 12 0 12 34 % R
% Ser: 0 34 0 34 45 34 0 45 12 12 12 12 0 0 0 % S
% Thr: 0 12 45 12 0 0 0 0 0 34 0 23 12 0 12 % T
% Val: 0 0 0 0 12 0 0 0 0 0 0 0 12 0 12 % V
% Trp: 0 0 0 12 0 0 0 0 0 0 0 12 0 12 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _