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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEPDC7 All Species: 24.55
Human Site: S168 Identified Species: 54
UniProt: Q96QD5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QD5 NP_001070710.1 511 58310 S168 F K S S D I R S A S L E D L W
Chimpanzee Pan troglodytes XP_001143476 511 58286 S168 F K S S D I R S A S L E D L W
Rhesus Macaque Macaca mulatta XP_001103700 529 61874 S160 E M W Y K R H S I A I G E V P
Dog Lupus familis XP_540553 502 57378 S160 F K S S D I K S A S L E D L W
Cat Felis silvestris
Mouse Mus musculus Q91WS7 511 58460 S168 F M S S D I K S D S L E D L W
Rat Rattus norvegicus Q4QR86 511 58183 S168 F K S S D I K S D S L E D L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506962 613 71080 M263 F N P S S I K M E S L E D F W
Chicken Gallus gallus XP_419630 519 59407 A168 F N T T P V K A E S L E D L W
Frog Xenopus laevis Q6AZT6 522 59673 S171 F Q S A S L Q S P S L E D L W
Zebra Danio Brachydanio rerio Q1JQ19 515 58739 T161 S N N S P V K T D K S L E D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788504 615 69605 E263 I P S L K I A E G R S S N M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 24.3 88.8 N.A. 87 87.8 N.A. 61.9 69.9 62.4 50.2 N.A. N.A. N.A. N.A. 29.5
Protein Similarity: 100 99.8 44.2 92.9 N.A. 94.1 94.1 N.A. 71.9 84 78.7 71 N.A. N.A. N.A. N.A. 45.3
P-Site Identity: 100 100 6.6 93.3 N.A. 80 86.6 N.A. 53.3 46.6 60 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 33.3 100 N.A. 86.6 93.3 N.A. 60 80 86.6 40 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 10 10 28 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 46 0 0 0 28 0 0 0 73 10 0 % D
% Glu: 10 0 0 0 0 0 0 10 19 0 0 73 19 0 0 % E
% Phe: 73 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 64 0 0 10 0 10 0 0 0 0 % I
% Lys: 0 37 0 0 19 0 55 0 0 10 0 0 0 0 10 % K
% Leu: 0 0 0 10 0 10 0 0 0 0 73 10 0 64 0 % L
% Met: 0 19 0 0 0 0 0 10 0 0 0 0 0 10 0 % M
% Asn: 0 28 10 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 10 10 0 19 0 0 0 10 0 0 0 0 0 10 % P
% Gln: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 19 0 0 10 0 0 0 0 0 % R
% Ser: 10 0 64 64 19 0 0 64 0 73 19 10 0 0 0 % S
% Thr: 0 0 10 10 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 19 0 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 73 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _