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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEPDC7 All Species: 30
Human Site: S179 Identified Species: 66
UniProt: Q96QD5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QD5 NP_001070710.1 511 58310 S179 E D L W E N L S L K P A N S P
Chimpanzee Pan troglodytes XP_001143476 511 58286 S179 E D L W E N L S L K P A N S P
Rhesus Macaque Macaca mulatta XP_001103700 529 61874 L171 G E V P A C R L V H R R Q L T
Dog Lupus familis XP_540553 502 57378 S171 E D L W E N L S L K P T N S P
Cat Felis silvestris
Mouse Mus musculus Q91WS7 511 58460 S179 E D L W E N L S L K P A S S P
Rat Rattus norvegicus Q4QR86 511 58183 S179 E D L W E N L S L K P T N S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506962 613 71080 S274 E D F W E N L S L K P A S S P
Chicken Gallus gallus XP_419630 519 59407 S179 E D L W E N L S L K P A N T P
Frog Xenopus laevis Q6AZT6 522 59673 S182 E D L W D N L S L T P A D P T
Zebra Danio Brachydanio rerio Q1JQ19 515 58739 L172 L E D V L G N L N M N T T I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788504 615 69605 N274 S N M K G I Q N P A F E D P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 24.3 88.8 N.A. 87 87.8 N.A. 61.9 69.9 62.4 50.2 N.A. N.A. N.A. N.A. 29.5
Protein Similarity: 100 99.8 44.2 92.9 N.A. 94.1 94.1 N.A. 71.9 84 78.7 71 N.A. N.A. N.A. N.A. 45.3
P-Site Identity: 100 100 0 93.3 N.A. 93.3 93.3 N.A. 86.6 93.3 66.6 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 20 93.3 N.A. 100 93.3 N.A. 93.3 100 80 6.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 10 0 55 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 73 10 0 10 0 0 0 0 0 0 0 19 0 0 % D
% Glu: 73 19 0 0 64 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 64 0 0 0 0 0 % K
% Leu: 10 0 64 0 10 0 73 19 73 0 0 0 0 10 0 % L
% Met: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 73 10 10 10 0 10 0 46 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 10 0 73 0 0 19 64 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 10 10 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 73 0 0 0 0 19 55 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 28 10 10 28 % T
% Val: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _