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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC7
All Species:
29.7
Human Site:
S222
Identified Species:
65.33
UniProt:
Q96QD5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QD5
NP_001070710.1
511
58310
S222
V
D
L
P
L
L
D
S
L
L
K
Q
Q
E
A
Chimpanzee
Pan troglodytes
XP_001143476
511
58286
S222
V
D
L
P
L
L
D
S
L
L
K
Q
Q
E
A
Rhesus Macaque
Macaca mulatta
XP_001103700
529
61874
S214
L
D
I
K
L
V
N
S
K
F
I
I
H
N
V
Dog
Lupus familis
XP_540553
502
57378
S214
V
D
L
S
L
L
D
S
L
L
Q
Q
R
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS7
511
58460
S222
V
D
L
P
F
L
D
S
L
L
K
Q
Q
E
V
Rat
Rattus norvegicus
Q4QR86
511
58183
L222
L
P
F
L
D
S
L
L
K
Q
Q
E
V
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506962
613
71080
S317
L
D
I
P
L
L
D
S
L
L
K
H
Q
K
M
Chicken
Gallus gallus
XP_419630
519
59407
S222
V
D
L
P
L
L
D
S
L
L
E
H
Q
A
V
Frog
Xenopus laevis
Q6AZT6
522
59673
S225
V
D
L
P
L
L
D
S
L
L
E
Y
T
P
V
Zebra Danio
Brachydanio rerio
Q1JQ19
515
58739
S215
I
E
L
P
L
L
E
S
L
L
E
G
Q
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788504
615
69605
N317
V
E
L
P
H
L
D
N
L
L
A
C
A
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
24.3
88.8
N.A.
87
87.8
N.A.
61.9
69.9
62.4
50.2
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
99.8
44.2
92.9
N.A.
94.1
94.1
N.A.
71.9
84
78.7
71
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
20
73.3
N.A.
86.6
0
N.A.
66.6
73.3
66.6
60
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
46.6
86.6
N.A.
86.6
20
N.A.
86.6
80
73.3
93.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
10
19
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
73
0
0
10
0
73
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
0
0
0
10
0
0
0
28
10
0
46
0
% E
% Phe:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
19
10
0
0
% H
% Ile:
10
0
19
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
19
0
37
0
0
10
0
% K
% Leu:
28
0
73
10
73
82
10
10
82
82
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
73
0
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
19
37
55
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
10
0
10
0
82
0
0
0
0
0
0
19
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
64
0
0
0
0
10
0
0
0
0
0
0
10
10
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _