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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC7
All Species:
20.61
Human Site:
S258
Identified Species:
45.33
UniProt:
Q96QD5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QD5
NP_001070710.1
511
58310
S258
R
G
I
L
K
A
Y
S
D
S
Q
E
D
E
W
Chimpanzee
Pan troglodytes
XP_001143476
511
58286
S258
R
G
I
L
K
A
Y
S
D
S
Q
E
D
E
W
Rhesus Macaque
Macaca mulatta
XP_001103700
529
61874
M247
P
H
W
V
L
S
A
M
K
C
L
A
N
W
P
Dog
Lupus familis
XP_540553
502
57378
S249
R
G
I
L
K
A
Y
S
D
S
Q
E
D
E
W
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS7
511
58460
G258
R
G
I
L
R
A
Y
G
D
S
Q
E
D
E
W
Rat
Rattus norvegicus
Q4QR86
511
58183
G256
R
G
I
L
R
A
Y
G
D
S
Q
E
D
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506962
613
71080
G353
R
E
I
L
K
A
Y
G
D
S
Q
A
D
E
W
Chicken
Gallus gallus
XP_419630
519
59407
S258
R
E
I
L
K
A
F
S
D
S
Q
T
D
E
W
Frog
Xenopus laevis
Q6AZT6
522
59673
S260
R
E
I
L
K
A
F
S
D
A
Q
A
D
E
W
Zebra Danio
Brachydanio rerio
Q1JQ19
515
58739
S252
R
E
I
L
K
A
F
S
E
A
Q
A
D
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788504
615
69605
D362
R
P
D
V
N
N
I
D
P
W
L
R
A
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
24.3
88.8
N.A.
87
87.8
N.A.
61.9
69.9
62.4
50.2
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
99.8
44.2
92.9
N.A.
94.1
94.1
N.A.
71.9
84
78.7
71
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
80
80
73.3
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
80
86.6
86.6
80
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
82
10
0
0
19
0
37
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
73
0
0
0
82
0
0
% D
% Glu:
0
37
0
0
0
0
0
0
10
0
0
46
0
73
0
% E
% Phe:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% F
% Gly:
0
46
0
0
0
0
0
28
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
82
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
64
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
82
10
0
0
0
0
0
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% Q
% Arg:
91
0
0
0
19
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
55
0
64
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
82
% W
% Tyr:
0
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _