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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEPDC7 All Species: 23.94
Human Site: S27 Identified Species: 52.67
UniProt: Q96QD5 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QD5 NP_001070710.1 511 58310 S27 A H R P P G F S V A Q K P F G
Chimpanzee Pan troglodytes XP_001143476 511 58286 S27 A H R P P G F S V A Q K P F G
Rhesus Macaque Macaca mulatta XP_001103700 529 61874 K27 T V E L F R A K M P L R K H R
Dog Lupus familis XP_540553 502 57378 T28 A Q K P F G A T Y V W S S I I
Cat Felis silvestris
Mouse Mus musculus Q91WS7 511 58460 S27 A Q R P P G F S V A Q K P F G
Rat Rattus norvegicus Q4QR86 511 58183 S27 A Q R P P G F S V A Q K P F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506962 613 71080 S121 S P S R A G F S V A Q K P F G
Chicken Gallus gallus XP_419630 519 59407 S27 A T R P P G F S L A Q K P F G
Frog Xenopus laevis Q6AZT6 522 59673 N27 S Q R P P G P N G S H R P F R
Zebra Danio Brachydanio rerio Q1JQ19 515 58739 V31 I N N L Q T Q V E V K R R R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788504 615 69605 T28 A T P I A G A T Q A P G P F R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 24.3 88.8 N.A. 87 87.8 N.A. 61.9 69.9 62.4 50.2 N.A. N.A. N.A. N.A. 29.5
Protein Similarity: 100 99.8 44.2 92.9 N.A. 94.1 94.1 N.A. 71.9 84 78.7 71 N.A. N.A. N.A. N.A. 45.3
P-Site Identity: 100 100 0 20 N.A. 93.3 93.3 N.A. 66.6 86.6 40 0 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 13.3 33.3 N.A. 93.3 93.3 N.A. 73.3 93.3 66.6 20 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 64 0 0 0 19 0 28 0 0 64 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 19 0 55 0 0 0 0 0 0 73 0 % F
% Gly: 0 0 0 0 0 82 0 0 10 0 0 10 0 0 55 % G
% His: 0 19 0 0 0 0 0 0 0 0 10 0 0 10 10 % H
% Ile: 10 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 10 0 0 0 0 10 0 0 10 55 10 0 0 % K
% Leu: 0 0 0 19 0 0 0 0 10 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 64 55 0 10 0 0 10 10 0 73 0 0 % P
% Gln: 0 37 0 0 10 0 10 0 10 0 55 0 0 0 0 % Q
% Arg: 0 0 55 10 0 10 0 0 0 0 0 28 10 10 28 % R
% Ser: 19 0 10 0 0 0 0 55 0 10 0 10 10 0 0 % S
% Thr: 10 19 0 0 0 10 0 19 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 10 46 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _