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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEPDC7 All Species: 4.55
Human Site: S287 Identified Species: 10
UniProt: Q96QD5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QD5 NP_001070710.1 511 58310 S287 M V V E I S R S F P E Q P D R
Chimpanzee Pan troglodytes XP_001143476 511 58286 S287 M V V E I S R S F P E Q P D R
Rhesus Macaque Macaca mulatta XP_001103700 529 61874 A276 K D V F K T I A D Y Y G H L K
Dog Lupus familis XP_540553 502 57378 N278 L V V D I S R N F P E Q P D R
Cat Felis silvestris
Mouse Mus musculus Q91WS7 511 58460 N287 M V V D I S R N F P E Q P D R
Rat Rattus norvegicus Q4QR86 511 58183 N285 M V V D I S R N F P E Q P D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506962 613 71080 N382 V V V D V S K N F P E Q P D K
Chicken Gallus gallus XP_419630 519 59407 N287 M V V D I S R N L P D Q L D K
Frog Xenopus laevis Q6AZT6 522 59673 N289 M V V D V S R N L P E Q Q A P
Zebra Danio Brachydanio rerio Q1JQ19 515 58739 G281 L V V D V S R G L A K C E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788504 615 69605 H391 D F C S S R T H T A G M L H A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 24.3 88.8 N.A. 87 87.8 N.A. 61.9 69.9 62.4 50.2 N.A. N.A. N.A. N.A. 29.5
Protein Similarity: 100 99.8 44.2 92.9 N.A. 94.1 94.1 N.A. 71.9 84 78.7 71 N.A. N.A. N.A. N.A. 45.3
P-Site Identity: 100 100 6.6 80 N.A. 86.6 86.6 N.A. 60 60 53.3 26.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 100 86.6 73.3 60 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 19 0 0 0 10 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 10 0 64 0 0 0 0 10 0 10 0 0 64 0 % D
% Glu: 0 0 0 19 0 0 0 0 0 0 64 0 10 10 10 % E
% Phe: 0 10 0 10 0 0 0 0 55 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 10 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 10 10 0 % H
% Ile: 0 0 0 0 55 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 10 0 10 0 0 0 10 0 0 0 28 % K
% Leu: 19 0 0 0 0 0 0 0 28 0 0 0 19 10 0 % L
% Met: 55 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 55 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 73 0 0 55 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 73 10 0 0 % Q
% Arg: 0 0 0 0 0 10 73 0 0 0 0 0 0 0 46 % R
% Ser: 0 0 0 10 10 82 0 19 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 10 0 10 0 0 0 0 0 0 % T
% Val: 10 82 91 0 28 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _