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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC7
All Species:
22.12
Human Site:
T135
Identified Species:
48.67
UniProt:
Q96QD5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QD5
NP_001070710.1
511
58310
T135
S
C
S
L
Y
R
F
T
T
I
P
N
Q
D
S
Chimpanzee
Pan troglodytes
XP_001143476
511
58286
T135
S
C
S
L
Y
R
F
T
T
I
P
N
Q
D
S
Rhesus Macaque
Macaca mulatta
XP_001103700
529
61874
K127
P
Y
Q
K
D
V
I
K
F
P
E
W
N
D
P
Dog
Lupus familis
XP_540553
502
57378
T127
S
C
S
L
Y
R
F
T
T
I
P
N
Q
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS7
511
58460
T135
S
C
S
L
Y
R
F
T
T
I
P
N
Q
D
N
Rat
Rattus norvegicus
Q4QR86
511
58183
T135
S
C
S
L
Y
R
F
T
T
I
P
N
Q
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506962
613
71080
T230
C
S
L
Y
R
F
T
T
M
T
S
Q
E
K
N
Chicken
Gallus gallus
XP_419630
519
59407
T135
S
S
S
L
Y
R
F
T
N
V
S
S
Q
V
D
Frog
Xenopus laevis
Q6AZT6
522
59673
N138
C
S
L
Y
R
F
L
N
S
S
N
L
L
G
V
Zebra Danio
Brachydanio rerio
Q1JQ19
515
58739
E128
T
P
S
T
S
G
S
E
T
I
G
S
G
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788504
615
69605
R230
R
H
S
I
G
L
G
R
T
A
K
F
D
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
24.3
88.8
N.A.
87
87.8
N.A.
61.9
69.9
62.4
50.2
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
99.8
44.2
92.9
N.A.
94.1
94.1
N.A.
71.9
84
78.7
71
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
6.6
53.3
0
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
20
66.6
6.6
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
19
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
10
55
10
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
19
55
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
10
10
10
0
0
0
10
0
10
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
0
55
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
10
0
0
10
0
% K
% Leu:
0
0
19
55
0
10
10
0
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
10
46
10
0
28
% N
% Pro:
10
10
0
0
0
0
0
0
0
10
46
0
0
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
10
55
0
0
% Q
% Arg:
10
0
0
0
19
55
0
10
0
0
0
0
0
10
0
% R
% Ser:
55
28
73
0
10
0
10
0
10
10
19
19
0
0
46
% S
% Thr:
10
0
0
10
0
0
10
64
64
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
10
0
19
55
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _