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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC7
All Species:
4.55
Human Site:
T241
Identified Species:
10
UniProt:
Q96QD5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QD5
NP_001070710.1
511
58310
T241
P
Q
P
K
R
Q
S
T
M
V
N
S
S
N
Y
Chimpanzee
Pan troglodytes
XP_001143476
511
58286
T241
P
Q
P
K
R
Q
S
T
M
V
N
S
S
N
Y
Rhesus Macaque
Macaca mulatta
XP_001103700
529
61874
V230
S
V
S
K
Q
G
V
V
I
L
D
D
K
S
K
Dog
Lupus familis
XP_540553
502
57378
D232
P
Q
P
K
R
Q
P
D
L
V
N
S
S
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS7
511
58460
D241
P
Q
S
K
R
Q
P
D
M
V
N
T
S
N
Y
Rat
Rattus norvegicus
Q4QR86
511
58183
D239
P
Q
S
K
R
Q
P
D
M
V
N
T
S
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506962
613
71080
E336
A
Q
Q
K
K
K
Q
E
L
I
N
T
S
N
Y
Chicken
Gallus gallus
XP_419630
519
59407
G241
P
Q
P
K
E
D
S
G
Y
V
I
T
S
N
Y
Frog
Xenopus laevis
Q6AZT6
522
59673
D243
I
P
N
V
K
E
E
D
H
N
L
T
S
N
Y
Zebra Danio
Brachydanio rerio
Q1JQ19
515
58739
D235
H
S
M
D
S
D
P
D
L
L
Y
T
S
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788504
615
69605
K345
P
N
L
N
T
P
A
K
R
M
S
S
R
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
24.3
88.8
N.A.
87
87.8
N.A.
61.9
69.9
62.4
50.2
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
99.8
44.2
92.9
N.A.
94.1
94.1
N.A.
71.9
84
78.7
71
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
6.6
80
N.A.
73.3
73.3
N.A.
40
60
20
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
40
86.6
N.A.
80
80
N.A.
73.3
66.6
40
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
19
0
46
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
0
10
10
10
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% I
% Lys:
0
0
0
73
19
10
0
10
0
0
0
0
10
0
10
% K
% Leu:
0
0
10
0
0
0
0
0
28
19
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
37
10
0
0
0
0
0
% M
% Asn:
0
10
10
10
0
0
0
0
0
10
55
0
0
73
10
% N
% Pro:
64
10
37
0
0
10
37
0
0
0
0
0
0
0
0
% P
% Gln:
0
64
10
0
10
46
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
46
0
0
0
10
0
0
0
10
10
0
% R
% Ser:
10
10
28
0
10
0
28
0
0
0
10
37
82
19
0
% S
% Thr:
0
0
0
0
10
0
0
19
0
0
0
55
0
0
0
% T
% Val:
0
10
0
10
0
0
10
10
0
55
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
82
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _