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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC7
All Species:
19.7
Human Site:
Y460
Identified Species:
43.33
UniProt:
Q96QD5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QD5
NP_001070710.1
511
58310
Y460
Q
R
I
D
Q
R
D
Y
S
N
N
T
E
K
T
Chimpanzee
Pan troglodytes
XP_001143476
511
58286
Y460
Q
R
I
D
Q
H
D
Y
S
N
N
T
E
K
T
Rhesus Macaque
Macaca mulatta
XP_001103700
529
61874
F440
R
Q
I
S
P
E
E
F
E
Y
Q
R
S
Y
G
Dog
Lupus familis
XP_540553
502
57378
Y451
Q
R
I
D
Q
S
D
Y
S
D
R
T
Q
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS7
511
58460
Y460
Q
R
I
D
E
S
E
Y
S
S
S
T
K
K
K
Rat
Rattus norvegicus
Q4QR86
511
58183
Y458
Q
R
I
D
G
R
E
Y
S
S
S
I
Q
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506962
613
71080
C555
Q
R
T
Q
Q
N
E
C
C
P
D
P
Q
K
T
Chicken
Gallus gallus
XP_419630
519
59407
Y461
Q
K
L
D
E
R
E
Y
R
L
N
T
E
K
T
Frog
Xenopus laevis
Q6AZT6
522
59673
F464
Q
R
V
D
K
R
E
F
D
S
A
A
Q
N
N
Zebra Danio
Brachydanio rerio
Q1JQ19
515
58739
F457
R
H
L
S
G
K
E
F
V
E
T
V
Q
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788504
615
69605
F562
Q
M
V
T
T
E
Q
F
E
V
E
D
Q
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
24.3
88.8
N.A.
87
87.8
N.A.
61.9
69.9
62.4
50.2
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
99.8
44.2
92.9
N.A.
94.1
94.1
N.A.
71.9
84
78.7
71
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
93.3
6.6
73.3
N.A.
53.3
53.3
N.A.
33.3
60
26.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
33.3
86.6
N.A.
86.6
80
N.A.
53.3
86.6
66.6
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
64
0
0
28
0
10
10
10
10
0
0
0
% D
% Glu:
0
0
0
0
19
19
64
0
19
10
10
0
28
0
0
% E
% Phe:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
55
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
10
10
0
0
0
0
0
0
10
73
19
% K
% Leu:
0
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
19
28
0
0
10
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
82
10
0
10
37
0
10
0
0
0
10
0
55
0
0
% Q
% Arg:
19
64
0
0
0
37
0
0
10
0
10
10
0
0
0
% R
% Ser:
0
0
0
19
0
19
0
0
46
28
19
0
10
0
0
% S
% Thr:
0
0
10
10
10
0
0
0
0
0
10
46
0
0
55
% T
% Val:
0
0
19
0
0
0
0
0
10
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
10
0
0
0
19
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _