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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC7
All Species:
21.52
Human Site:
Y498
Identified Species:
47.33
UniProt:
Q96QD5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QD5
NP_001070710.1
511
58310
Y498
K
K
L
L
G
Q
F
Y
K
C
H
P
D
I
F
Chimpanzee
Pan troglodytes
XP_001143476
511
58286
Y498
K
K
L
L
G
Q
F
Y
K
C
H
P
D
I
F
Rhesus Macaque
Macaca mulatta
XP_001103700
529
61874
Q478
K
K
K
L
K
Q
F
Q
K
S
Y
P
E
V
Y
Dog
Lupus familis
XP_540553
502
57378
Y489
K
K
L
L
G
Q
F
Y
K
C
H
P
D
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS7
511
58460
R498
K
K
L
L
G
Q
F
R
K
T
H
P
D
I
F
Rat
Rattus norvegicus
Q4QR86
511
58183
H496
K
K
L
L
G
Q
F
H
K
S
H
P
D
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506962
613
71080
Y593
K
K
L
L
G
Q
F
Y
K
S
H
P
N
I
F
Chicken
Gallus gallus
XP_419630
519
59407
H499
K
R
L
L
G
Q
F
H
S
S
N
P
S
I
F
Frog
Xenopus laevis
Q6AZT6
522
59673
Y502
K
R
L
L
G
Q
F
Y
K
S
H
P
E
T
F
Zebra Danio
Brachydanio rerio
Q1JQ19
515
58739
Y495
R
R
L
L
G
Q
F
Y
K
G
H
P
E
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788504
615
69605
Q600
K
Q
K
L
K
M
L
Q
K
A
H
P
D
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
24.3
88.8
N.A.
87
87.8
N.A.
61.9
69.9
62.4
50.2
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
99.8
44.2
92.9
N.A.
94.1
94.1
N.A.
71.9
84
78.7
71
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
46.6
100
N.A.
86.6
86.6
N.A.
86.6
60
73.3
73.3
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
73.3
100
N.A.
86.6
93.3
N.A.
93.3
80
86.6
93.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% E
% Phe:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
82
% F
% Gly:
0
0
0
0
82
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
82
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
82
0
% I
% Lys:
91
64
19
0
19
0
0
0
91
0
0
0
0
0
0
% K
% Leu:
0
0
82
100
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
10
0
0
0
91
0
19
0
0
0
0
0
0
0
% Q
% Arg:
10
28
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
46
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
10
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _