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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PURB All Species: 36.36
Human Site: S121 Identified Species: 80
UniProt: Q96QR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QR8 NP_150093.1 312 33241 S121 G P R R A L K S E F L V R E N
Chimpanzee Pan troglodytes XP_001136727 295 32969 S118 E P R R A L K S E F L V R E N
Rhesus Macaque Macaca mulatta XP_001085613 304 33781 S127 E P R R A L K S E F L V R E N
Dog Lupus familis XP_850017 341 36742 S159 G P R R A L K S E F L V R E N
Cat Felis silvestris
Mouse Mus musculus O35295 324 33883 S133 G P R R A L K S E F L V R E N
Rat Rattus norvegicus Q68A21 315 33399 S124 G P R R A L K S E F L V R E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426295 336 38538 T162 H P H S V L K T E Y I E R D N
Frog Xenopus laevis Q8AVS4 328 34968 S125 G P R R A L K S E F L V R E N
Zebra Danio Brachydanio rerio Q6PHK6 297 32588 S117 G P R R A L K S E F L V R E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784262 259 29404 Y92 L T D F S E H Y A Q L G P A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKZ1 296 32182 S125 F L K V S E A S V S R N R S T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 70.5 82.1 N.A. 94.4 97.1 N.A. N.A. 51.4 81.7 83 N.A. N.A. N.A. N.A. 45.8
Protein Similarity: 100 79.1 79.1 83.5 N.A. 95.3 97.4 N.A. N.A. 64.2 86.2 87.8 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 93.3 93.3 100 N.A. 100 100 N.A. N.A. 40 100 100 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 100 N.A. N.A. 66.6 100 100 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 73 0 10 0 10 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 19 0 0 0 0 19 0 0 82 0 0 10 0 73 0 % E
% Phe: 10 0 0 10 0 0 0 0 0 73 0 0 0 0 0 % F
% Gly: 55 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 10 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 82 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 0 0 82 0 0 0 0 82 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 91 % N
% Pro: 0 82 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 73 73 0 0 0 0 0 0 10 0 91 0 0 % R
% Ser: 0 0 0 10 19 0 0 82 0 10 0 0 0 10 0 % S
% Thr: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % T
% Val: 0 0 0 10 10 0 0 0 10 0 0 73 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _